纳络酮合并血塞通治疗老年性脑梗塞的可行性研究  

Feasibility Study of Naloxone Combined with Xuesaitong in the Treatment of Senile Cerebral Infarction

作　　者：陈臻[1] CHEN Zhen(Department of Neurology, Traditional Chinese Medicine and Western Medicine Hospital, Dazhou Si chuan, 635000 China)

机构地区：[1]达州市中西医结合医院科室神经内科,四川达州635000

出　　处：《中外医疗》2019年第7期130-132,共3页China & Foreign Medical Treatment

摘　　要：目的对纳络酮合并血塞通治疗老年性脑梗塞的可行性进行研究。方法方便选取2015年2月—2017年2月期间收治的116例老年性脑梗塞患者,随机分为对照组(n=58)与观察组(n=58),两组患者均采用常规治疗,对照组在常规治疗基础上添加纳络酮治疗,观察组在常规治疗基础上添加纳络酮合并血塞通治疗。对两组患者的临床治疗效果、不良反应等进行比较。结果治疗前两组患者神经功能缺损情况、日常生活能力评分比较,差异无统计学意义(P>0.05)。治疗后观察组患者神经功能缺损评分、日常生活能力评分分别为(9.96±2.06)分、(85.54±4.74)分,均优于对照组(15.43±2.87)分、(70.15±4.85)分(t=11.792、17.283,P<0.05),观察组临床治疗总有效率、不良反应发生率、患者家属满意度分别为100.0%、3.45%、94.83%,均优于对照组93.10%、13.79%、79.31%(χ~2=4.143、3.940、6.202,P<0.05)。结论纳络酮合并血塞通治疗老年性脑梗塞具有可行性,可改善患者临床治疗效果、神经功能缺损以及生活能力,降低医患纠纷事件发生率,具有显著临床价值。Objective To study the feasibility of naloxone combined with Xuesaitong in the treatment of senile cerebral infarction. Methods 116 patients with senile cerebral infarction who were convenient admitted between February 2015 and February 2017 were randomly divided into control group(n=58) and observation group(n=58). Both groups received routine treatment. The control group was treated with naloxone on the basis of conventional treatment, and the observation group was treated with naloxone combined with Xuesaitong on the basis of conventional treatment. The clinical treatment effects and adverse reactions of the two groups of patients were compared. Results There were no significant differences in neurological deficits and daily living ability scores between the two groups before treatment(P>0.05). After treatment, the neurological deficit score and daily living ability score of the observation group were(9.96±2.06)points and(85.54±4.74)points,respectively, which were better than the control group(15.43±2.87)points and(70.15±4.85)points.(t=11.792、17.283 P<0.05). The total effective rate, adverse reaction rate and patient satisfaction of the observation group were 100.0%, 3.45%and 94.83%, respectively, which were better than the control group 93.10% and 13.79%, 79.31%(χ^2=4.143, 3.940, 6.202,P<0.05). Conclusion Naloxone combined with Xuesaitong is feasible for the treatment of senile cerebral infarction, which can improve the clinical treatment effect, neurological deficit and life ability, and reduce the incidence of medical disputes.It has significant clinical value.

关 键 词：纳络酮 血塞通 老年性脑梗塞 可行性研究 

分 类 号：R5[医药卫生—内科学]