经皮椎体成形术治疗骨质疏松性椎体压缩性骨折的效果分析  

Effect analysis of percutaneous vertebroplasty for osteoporotic vertebral compression fractures

作　　者：邝立鹏[1] 江山岳[1] 张炜[1] KUANG Li-peng;JIANG Shan-yuae;ZHANG Wei(Department of Orthopaedics, Zhuhai Hospital Affiliated to Zunyi Medical College, Zhuhai 519100, China)

机构地区：[1]遵义医学院第五附属(珠海)医院骨二科,519100

出　　处：《中国现代药物应用》2019年第8期25-27,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析骨质疏松性椎体压缩性骨折(OVCF)患者行经皮椎体成形术(PVP)治疗的临床效果。方法 80例OVCF患者,根据入院顺序分为对照组和观察组,每组40例。对照组患者采用传统保守治疗,观察组患者采用PVP治疗。比较两组患者手术前、手术后随访6个月疼痛程度、脊柱后凸Cobb角、Oswesty功能障碍指数(ODI)、伤椎椎体前缘及中部高度。结果手术前,两组患者视觉模拟评分法(VAS)评分、脊柱后凸Cobb角、ODI、伤椎椎体前缘及中部高度比较差异无统计学意义(P>0.05);手术后随访6个月,两组患者的VAS评分、脊柱后凸Cobb角、ODI均较本组手术前明显降低,伤椎椎体前缘及中部高度较本组手术前显著升高,差异具有统计学意义(P<0.05);观察组VAS评分(1.60±0.87)分、脊柱后凸Cobb角(7.59±3.27)°、ODI(18.54±6.09)低于对照组的(2.63±1.25)分、(10.72±4.06)°、(23.01±7.80),伤椎椎体前缘高度(26.46±3.38)mm及伤锥中部高度(27.98±3.25)mm高于对照组的(22.01±2.13)、(20.85±2.01)mm,差异具有统计学意义(P<0.05)。结论对于OVCF患者,采用PVP治疗可有效缓解其疼痛,在矫正后凸畸形、促进伤椎恢复的基础上,加快患者脊椎功能的恢复,值得临床推广及应用。Objective To analyze the clinical effect of percutaneous vertebroplasty(PVP)for the treatment of patients with osteoporotic vertebral compression fractures(OVCF). Methods A total of 80 OVCF patients were divided by visiting order into control group and observation group, with 40 cases in each group. The control group was treated with traditional conservative therapy, and the observation group was treated with PVP. Comparison were made on pain level, kyphosis Cobb angle, Oswesty dysfunction index(ODI), front and middle height of injured vertebral body before operation and after 6 months of follow-up between the two groups. Results Before operation, both groups had no statistically significant difference in visual analogue scale(VAS) score, kyphosis Cobb angle, ODI and front and middle height of injured vertebral body(P>0.05). After 6 months of follow-up, both groups had obviously lower VAS score, kyphosis Cobb angle and ODI than those before operation, and significantly higher front and middle height of injured vertebral body than those before operation. Their difference was statistically significant(P<0.05). The observation group had lower VAS score as(1.60±0.87) points, kyphosis Cobb angle as(7.59±3.27)° and ODI as(18.54±6.09) than(2.63±1.25) points,(10.72±4.06)° and(23.01±7.80) in the control group, and higher front height of injured vertebral body as(26.46±3.38) mm and middle height of injured vertebral body as(27.98±3.25) mm than(22.01±2.13) and(20.85±2.01) mm in the control group. Their difference was statistically significant(P<0.05). Conclusion For OVCF patients, PVP therapy can effectively alleviate the pain and accelerate the recovery of vertebral function on the basis of correcting kyphosis deformity and promote the recovery of injured vertebrae. It is worthy of clinical promotion and application.

关 键 词：骨质疏松性椎体压缩性骨折 经皮椎体成形术 临床效果 

分 类 号：R687.3[医药卫生—骨科学]