冠心病合并心律失常的药物治疗方法分析  

Analysis of Drug Therapy for Coronary Heart Disease Complicated With Arrhythmia

作　　者：徐业成[1] XU Yecheng(Department of Cardiology,Xiaogan Central Hospital,Xiaogan Hubei 432100,China)

机构地区：[1]孝感市中心医院心内科,湖北孝感432100

出　　处：《中国继续医学教育》2019年第12期131-133,共3页China Continuing Medical Education

摘　　要：目的评价胺碘酮与美托洛尔在老年冠心病并发心律失常治疗中的应用效果。方法选取2016年8月—2017年8月我院收治的老年冠心病患者90例作为研究对象。采用随机数字表法的分组形式,将其平均分为两组,即实验组与对照组,每组均45例患者。对照组采用胺碘酮,实验组在此基础上,联合使用美托洛尔,对比两组患者的治疗效果以及治疗前后QTD与心率指标。结果实验组患者的治疗有效率为97.8%,对照组为77.8%。对照组低于实验组,组间对比,差异具有统计学意义(P <0.05)。治疗后,实验组患者的QTD以及心率指标优于对照组,组间比较,差异具有统计学意义(P <0.05)。对照组患者不良反应总发生率高于实验组,组间对比,差异具有统计学意义(P<0.05)。结论在老年冠心病并发心律失常治疗过程中,采用胺碘酮联合美托洛尔治疗,能够加快康复速度,提升安全性。Objective To evaluate the effect of amiodarone and metoprolol in the treatment of senile coronary heart disease complicated with arrhythmia.Methods 90 elderly patients with coronary heart disease admitted to our hospital from August 2016 to August 2017 were selected as the study subjects.Random number table method was used to divide the patients into two groups,the experimental group and the control group,with 45 patients in each group.The control group was treated with amiodarone. On this basis,the experimental group used metoprolol in combination. The therapeutic effect,QTD and heart rate before and after treatment were compared between the two groups.Results The effective rate was 97.8% in the experimental group and 77.8% in the control group.The control group was lower than the experimental group,and the difference was statistically significant (P<0.05).After treatment,the indexes of QTD and heart rate in the experimental group were better than those in the control group,and the difference was statistically significant (P<0.05).The total incidence of adverse reactions in the control group was higher than that in the experimental group.There was a significant difference between the two groups (P<0.05).Conclusion Amiodarone combined with metoprolol in the treatment of elderly coronary heart disease complicated with arrhythmia can speed up the recovery rate,enhance the safety.

关 键 词：胺碘酮 美托洛尔 老年冠心病 心律失常 应用效果 价值 

分 类 号：R541[医药卫生—心血管疾病]