美托洛尔用于急性冠脉综合征患者的评价  

Evaluation of the Application of Metoprolol in Patients with Acute Coronary Syndrome

作　　者：蒋军[1] 夏宗玲[1] JIANG Jun;XIA Zongling(Department of Pharmacy, the First People's Hospital of Changzhou City, Jiangsu Province, Changzhou 213003, China)

机构地区：[1]江苏省常州市第一人民医院药剂科,常州213003

出　　处：《医药导报》2019年第5期646-649,共4页Herald of Medicine

摘　　要：目的建立美托洛尔药物利用评价(DUE)标准,并用于评价美托洛尔使用合理性,为临床合理用药提供参考。方法参考DUE的建立方法,建立美托洛尔DUE标准,采用回顾性研究方法,选取江苏省常州市第一人民医院91例急性冠状动脉综合征患者的医嘱,进行用药评价与分析,并提出干预措施及整改意见。结果根据所建立的美托洛尔DUE标准,分别从用药指征、用药过程、用药结果 3个方面进行分析评价,发现该院美托洛尔用药时机、剂量间隔与调整、联合用药、药学监护等方面均较为合理。结论美托洛尔DUE可有效协助临床药师在药物治疗前、治疗过程中及时监测美托洛尔的应用合理性,并综合评价药物治疗效果。DUE可作为临床药师开展工作的有效手段。Objective To establish the metoprolol drug use evaluation (DUE) criteria, so as to evaluate the use of metoprolol and provide reference for clinical rational use. Methods According with the reference of establishing DUE, the evaluation criteria of metoprolol drug utilization were established. The retrospective study was conducted to evaluate and analysis the medical prescriptions of 91 patients with acute coronary syndrome in the First People's Hospital of Changzhou City. Interventions and improvements were concluded based on the analyze. Results According to the established metoprolol DUE criteria, the analysis were conducted from 3 aspects: the drug indications, medication process and the treatment outcome.The result showed our hospital did good job on the rational use of metoprolol in the fields of medication timing, dose interval and adjustment, combination therapy and pharmaceutical care. Conclusion The DUE of metoprolol can effectively assist clinical pharmacists to monitor the use of metoprolol before and during the course of treatment. It can be an effective method for clinical pharmacists to evaluate the effect of treatment and rationality.

关 键 词：美托洛尔 药物利用评价 评价标准 合理用药 

分 类 号：R972.4[医药卫生—药品] R969.3[医药卫生—药学]