家畜防御素体内组织表达及体外表达研究进展  

Research Advances on In Vivo Tissue Expression and In Vitro Expression of Defensin in Livestock

作　　者：魏薇 李海军[1] 王鑫[1] 张齐政 曹贵方[1] WEI Wei;LI Hai-jun;WANG Xin;ZHANG Qi-zheng;CAO Gui-fang(College of Veterinary Medicine,Inner Mongolia Agricultural University,Hohhot 010018,China)

机构地区：[1]内蒙古农业大学兽医学院,内蒙古呼和浩特010018

出　　处：《畜牧与饲料科学》2019年第4期52-57,共6页Animal Husbandry and Feed Science

基　　金：国家自然科学基金项目(31660701;31360283)

摘　　要：防御素是广泛分布于动物、植物、昆虫体内的一类富含半胱氨酸的阳离子内源性抗菌肽,在动物免疫调节及植物自身防御方面扮演着重要的角色。对防御素的概念、类型、结构特征、作用机理进行了综述,总结了防御素在牛、马、羊、猪、鹿、骆驼等家畜体内组织表达及体外表达研究进展,并对防御素在未来生物制药和畜牧饲料生产方面的应用前景进行了展望。Defensin is cationic,endogenous and cysteine enriched antimicrobial peptide which is widely distributed in animals,plants and insects.It plays an important role in animal immune regulation and plant defense.This paper reviews the concept,type,structure and action mechanism of defensin,summarizes the research progress of in vivo tissue expression and in vitro expression of defensin in cattle,horse,sheep,pig,deer and camel,and prospects the future applications of defensin in biopharmaceutical industry and livestock feed production.

关 键 词：家畜 防御素 组织表达分布 体外表达 

分 类 号：S852.2[农业科学—基础兽医学]