广西地区特禀质儿童肺炎易患因素分析  

Analysis of the risk factors of pneumonia in intrinsic-quality children in Guangxi

作　　者：周志宁 李洁 姚勇志[2] 王力宁[2] 李志锋[2] 蒙春雪 杨黎明 蔡晓静[5] 莫雪莹 黎丽 黄志碧 张晓春[2] 孙继超 梁廷君 苏文静 ZHOU Zhining;LI Jie;YAO Yongzhi;WANG Lining;LI Zhifeng;MENG Chunxue;YANG Liming;CAI Xiaojing;MO Xueying;LI Li;HUANG Zhibi;ZHANG Xiaochun;SUN Jichao;LIANG Tingjun;SU Wenjing(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530023,China)

机构地区：[1]广西中医药大学第一临床医学院 [2]广西中医药大学第一附属医院儿科 [3]柳州市妇幼保健院中医科,广西柳州545000 [4]岑溪市中医医院儿科,广西岑溪543200 [5]北海市中医医院儿科,广西北海536000 [6]广西医科大学基础医学院教研室,南宁530023

出　　处：《中国中西医结合儿科学》2019年第2期96-100,共5页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015040);广西名中医民族医传承工作室建设项目(桂卫中[2013]10号)

摘　　要：目的探讨广西地区特禀质儿童社区获得性肺炎(CAP)的易患因素,为特禀质儿童社区获得性肺炎的防治提供临床循证依据。方法采用问卷调查的方法,于2017年4月至2018年9月在岑溪市、柳州市、北海市、三江县及南宁市招募1～6岁的儿童进行调查问卷。以既往是否患CAP作为因变量,以被调查的特禀质儿童的39个可能与CAP的易患因素及体质类型作为自变量,对特禀质儿童组的CAP相关易感因素进行逐步Logistic回归分析。结果调查收集的有效问卷共466份,其中343例为特禀质,兼积热质104例,兼气虚质66例,兼阴虚质38例,兼痰湿质16例,兼阳虚质13例。343例特禀质儿童,既往有患CAP病史者214例(62.4%),无CAP病史的129例(37.6%);非特禀质123例,其中有CAP病史38例(30.9%),无CAP病史85例(69.1%);经逐步Logistic回归分析发现,特禀质儿童CAP与既往有哮喘、反复呼吸道感染、营养不良等基础疾病、既往住院史及抗生素的使用差异有统计学意义(P<0.05);特禀质儿童患CAP的次数与特禀质兼痰湿质有关。结论特禀质儿童与CAP可能有密切相关性;既往有哮喘、反复呼吸道感染、营养不良基础病以及抗生素药物使用是特禀质儿童CAP易患因素;特禀质合并痰湿质的儿童患CAP的次数高于其他体质类型儿童。Objective To study the risk factors of community-acquired pneumonia(CAP) in intrinsic-quality children in Guangxi in order to provide clinical evidence-based basis for its prevention and treatment. Methods A questionnaire survey was performed in the children aged one to six years in the cities of Chenxi, Liuzhou, Beihai and Nanning as well as in Sanjiang county from April 2017 to September 2018.The dependent variable was whether the children had had CAP before, and the independent variable is the 39 possibilities of the intrinsic-quality children, the risk factors of CAP and the constitute type. The gradual Logistic regression analysis was made on the CAP-related risk factors in these children. Results A total of 466 valid questionnaires were collected, among which there were 343 cases of intrinsic quality,104 cases combined with accumulation of heat, 66 cases with qi-deficiency, 38 with yin-deficiency,16 with phlegm-dampness, and 13 with yang-deficiency. In the 343 children,214(62.4%) had had CAP,129(37.6%) had had no CAP;in the 123 children with non-intrinsic-quailty,38 had had CAP(30.9%),85 had had no CAP(69.1%), the gradual Logistic regression analysis showed that there was statistically significant relationship between intrinsic-quality children with CAP and the following factors: history of asthma,recurrent respiratory tract infection, the basic diseases such as malnutrition, hospitalization history and use of antibiotics( P <0.05);the incidence of CAP in the intrinsic-quality children was related to intrinsic quality combined with phlegm-dampness. Conclusion There may be close relationship between intrinsic quality and CAP in children;the risk factors of CAP in these children are:combination with asthma, recurrent respiratory tract infection, malnutrition and other basic diseases, and use of antibiotics;the incidence of CAP is higher in the children combined with phlegm-dampness than in those with other constitutions.

关 键 词：肺炎 特禀质 易患因素 回归分析 儿童 

分 类 号：R725.6[医药卫生—儿科]