肉桂醛对宫颈癌细胞中TNF-a表达影响的研究  

Effect of Cinnamaldehyde on TNF-a Expression in Cervical Cancer Cells

作　　者：尹兴忠[1] 赵冬梅[2] 杨智[3] 苗智[1] Yin Xingzhong;Zhao Dongmei;Yang Zhi;Miao Zhi(Jiamusi University Jiamusi 154007;First Affiliated Hospital of Jiamusi University, Jiamusi 154007;Second Affiliated Hospital of Jiamu University, Jiamusi 154007, China)

机构地区：[1]佳木斯大学基础医学院,黑龙江佳木斯154007 [2]佳木斯大学附属第一医院,黑龙江佳木斯154007 [3]佳木斯大学附属第二医院,黑龙江佳木斯154007

出　　处：《广东化工》2019年第7期46-46,45,共2页Guangdong Chemical Industry

基　　金：黑龙江省卫生厅项目(2013214);佳木斯大学项目(13Z1201533)

摘　　要：目的:研究TNF-a在宫颈癌细胞中的表达及肉桂醛对其表达的影响。方法:体外培养宫颈癌细胞,分为三组分别用不同浓度的肉桂醛干预,用HE染色、MTT、Western blot法观察不同浓度的肉桂醛对宫颈癌细胞生长的影响。结论:TNF-a在宫颈癌中起到总要作用,肉桂醛能降低TNF-a表达,对宫颈癌有治疗作用。Objective: To study the expression of TNF-α in cervical cancer cells and the effect of Cinnamaldehyde on its expression. Methods: Cervical cancer cells were cultured in vitro and divided into three groups with different concentrations of Cinnamaldehyde intervention. The effects of different concentrations of Cinnamaldehyde on the growth of cervical cancer cells were observed with HE staining, MTT, and Western blue. Conclusion: TNF-α plays an important role in cervical cancer. Cinnamaldehyde can reduce TNF-α expression and has therapeutic effect on cervical cancer.

关 键 词：肉桂醛 宫颈癌 TNF-Α 

分 类 号：TQ[化学工程]