老年尿路感染患者血清PCT、CRP水平变化及其临床意义  

Changes of PCT and CRP Levels in Elderly Patients with Urinary Tract Infection and their Clinical Significance

作　　者：习明[1] 程璐[1] 江文聪 华伟[1] 周宇林[1] 万颂 XI Ming;CHENG Lu;JlANG Wen-cong(Department of Urology,Huadu district Poeples Hospital Affiliated to Southern Medical University,Guangzhou 510800,China)

机构地区：[1]南方医科大学附属广州花都区人民医院泌尿外科,广东广州510800

出　　处：《医学临床研究》2019年第3期498-500,共3页Journal of Clinical Research

摘　　要：【目的】分析老年尿路感染患者血清降钙素原(PCT)和C反应蛋白(CRP)水平的变化及其临床意义。【方法】选择2017年1月至2018年10月本院收治68例老年尿路感染患者的临床资料,根据尿路感染部位分为上尿路感染(A组,n=32)和下尿路感染(B组,n=36),选择同期于本院健康体检正常的30例志愿者作为对照组(C组)。检测各组血、尿白细胞计数(WBC)及血清PCT、CRP水平,并对PCT、CRP水平进行相关性分析。【结果】A组、B组血WBC、尿WBC及血清PCT、CRP水平均显著高于C组,且A组血清PCT、CRP水平均显著高于B组,差异具有统计学意义(P<0.05)。治疗后A组、B组血清PCT、CRP水平均显著低于治疗前,且A组血清PCT、CRP水平高于B组,差异具有统计学意义(P<0.05)。Pearson相关性分析显示,血清PCT水平与CRP呈显著正相关(r=0.73,P=0.009<0.05)。【结论】血清PCT、CRP水平联合检测可较好的辅助诊断老年尿路感染发生情况,有助于临床用药,值得在临床实践中推广应用。[Objective] To analyze the changes of procalcitonin(PCT)and C-reactive protein(CRP)levels in urinary tract infection of elder patients and its clinical significance.[Methods]The clinical data of 68 elderly patients with urinary tract infections admitted to our hospital from January 2017 to October 2018 were selected.They were divided into upper urinary tract infections(group A,n=32)and lower urinary tract infections(group B,n=36)according to the location of urinary tract infections.Thirty healthy volunteers with normal physical examination in our hospital during the same period were selected as control group(group C).Blood and urine white blood cell count(WBC)and serum PCT and CRP levels were measured,and the correlation between PCT and CRP levels was analyzed.[Results]The levels of WBC in blood,WBC in urine,PCT and CRP in serum of the group A and the group B were significantly higher than those of thegroup C,and the levels of PCT and CRP in serum of the group A were significantly higher than those of the group B,with statistical significance(P<0.05).The levels of serum PCT and CRP in the group A and B after treatment were significantly lower than those before treatment,and the levels of serum PCT and CRP in the group A were higher thanthose in the group B,with statistical significance(P<0.05).Pearson correlation analysis showed that serum PCT level was positively correlated with CRP(r=0.73,P=0.009<0.05).[Conclusion]The combined detection of serum PCT and CRP levels can help to diagnose the occurrence of urinary tract infections in the elderly,and is helpful to clinical medication.It is worth popularizing and applying in clinical practice.

关 键 词：泌尿道感染/血液 C反应蛋白质/分析 降钙素/分析 

分 类 号：R691.3[医药卫生—泌尿科学]