狼疮样综合征研究进展  

Lupus-like syndrome

作　　者：张梦奇(综述)[1] 宋红梅(审校)[1] Zhang Mengqi;Song Hongmei(Department of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院儿科,100730

出　　处：《国际儿科学杂志》2019年第3期155-158,共4页International Journal of Pediatrics

摘　　要：狼疮样综合征是多种原因引起的系统性红斑狼疮(systemic lupus erythematosus,SLE)样临床表现及抗核抗体谱阳性一类疾病的总称。在儿童中,基因突变所致的原发性免疫缺陷病是引起狼疮样综合征的特有病因,另外,各种感染、药物及肿瘤等均可引起SLE样临床表现。目前治疗以原发病治疗为主,根据患儿情况决定是否使用免疫抑制剂。Lupus-like syndrome is characterized by positive anti-nuclear antibody and clinical manifestations similar with systemic lupus erythematosus (SLE). Primary immunodeficiencies (PID) are specific underlying causes of lupus-like syndrome in children. Various infections, drugs, and tumors can also have manifestations like SLE. Treatment for the underlying disease is recommended. Whether immunosuppressive thera. pies should be initiated depending on the condition of the patient.

关 键 词：狼疮样综合征 系统性红斑狼疮 原发性免疫缺陷病 副肿瘤综合征 

分 类 号：R135.120.6[医药卫生—劳动卫生]