儿童血栓相关性疾病溶栓治疗进展  

Progress in thrombolytic therapy for thrombosis-related diseases in children

作　　者：朱玲[1] 李莺[1] Zhu Ling;Li Ying(Department of PICU, Children' s Hospital of Soochow University, Suzhou 215025, China)

机构地区：[1]苏州大学附属儿童医院PICU,215025

出　　处：《中国小儿急救医学》2019年第3期175-178,共4页Chinese Pediatric Emergency Medicine

摘　　要：儿童血栓相关性疾病发病率逐渐升高,其危险因素包括中心静脉置管、感染、创伤等,最常见的并发症为血栓后综合征,导致肢体疼痛、肿胀,严重影响生活质量。溶栓治疗常应用重组组织型纤溶酶原激活剂,以导管导向溶栓、经皮药物机械溶栓等方式改善血管再通。溶栓治疗在成人患者中已得到广泛应用,但儿童患者中治疗经验尚不足,本文将从溶栓适应证、禁忌证、剂量、方式等方面综述儿童溶栓治疗的进展。The incidence of thrombosis-related diseases in children is gradually increasing.Risk factors include central venous catheterization, infection, trauma and so on.The most common complication is post-thrombotic syndrome, which causes limb pain and swelling and seriously affects the quality of life.Recombinant tissue plasminogen activator is often used in thrombolytic therapy to improve vascular recanalization by catheter-directed thrombolysis and percutaneous drug mechanical thrombolysis.Thrombolytic therapy has been widely used in adult patients, but the experience of treatment in children is not enough.This article reviewed the progress of thrombolytic therapy in children from indications, contraindications, dosage and methods of thrombolytic therapy.

关 键 词：深静脉血栓 血栓形成 血栓溶解 儿童 

分 类 号：R725.4[医药卫生—儿科]