血常规和前降钙素检测对儿科抗生素合理应用的影响研究  

Effect of blood routine and procalcitonin test on rational application of antibiotics in pediatrics

作　　者：马敬斌[1] 盛方红[1] 王道方[1] 庄明凤[1] MA Jing-bin;SHENG Fang-hong;WANG Dao-fang(Department Three of Pediatrics, Shandong Liaocheng Second People' s Hospital, Liaocheng 252601, China)

机构地区：[1]山东省聊城市第二人民医院小儿三科,252601

出　　处：《中国实用医药》2019年第10期34-35,共2页China Practical Medicine

摘　　要：目的研究血常规和前降钙素检测对儿科抗生素合理应用的影响,以指导抗生素的合理化使用。方法 80例上呼吸道感染患儿,采用随机数字表法分为对照组和观察组,每组40例。对照组患儿给予常规治疗,观察组患儿给予血常规和前降钙素检测,并根据测量结果进行相应的抗生素治疗。观察比较两组患儿的治疗费用和抗生素不良反应发生情况。结果观察组患儿抗菌药物费用及总费用分别为(43.4±5.3)、(87.5±9.7)元,均明显少于对照组的(78.5±6.4)、(127.9±9.8)元,差异均有统计学意义(t=26.715、18.531, P<0.05)。观察组患儿的抗生素不良反应发生率为12.50%(5/40),明显低于对照组的42.50%(17/40),差异有统计学意义(χ~2=9.028, P=0.003<0.05)。结论采用血常规和前降钙素检测对患儿进行抗生素治疗,可以显著提升临床疗效,降低治疗费用和不良反应发生率,减轻患儿家庭的负担,适合临床推广应用。Objective To study the effect of blood routine and procalcitonin test on rational application of antibiotics in pediatrics, so as to guide the rational use of antibiotics. Methods A total of 80 children with upper respiratory tract infection were divided by random number table method into control group and observation group, with 40 cases in each group. The control group received conventional therapy, and the observation group received blood routine and procalcitonin test, and antibiotic treatment was carried out according to the measurement results. The treatment costs and occurrence of adverse antibiotics reactions between the two groups was observed and compared. Results The observation group had obviously higher antibiotics costs and total costs respectively as(43.4±5.3) and(87.5±9.7) yuan than(78.5±6.4) and(127.9±9.8) yuan in the control group, and the difference was statistically significant(t=26.715, 18.531, P<0.05). The observation group had obviously lower incidence of adverse antibiotics reactions as 12.50%(5/40) than 42.50%(17/40) in the control group, and the difference was statistically significant(χ^2=9.028, P=0.003<0.05). Conclusion Antibiotic treatment of children with blood routine and procalcitonin can significantly improve clinical efficacy, reduce treatment costs and incidence of adverse reactions, reduce the burden on families, and is suitable for clinical application.

关 键 词：血常规 前降钙素检测 儿科 抗生素 合理应用 

分 类 号：R725.6[医药卫生—儿科]