子宫内膜异位症相关恶性肿瘤的研究进展  

Research progress of endometriosis associated malignancies

作　　者：钱欢欢[1] 戴辉华[1] 林明娟 王秀丽[1] Qian Huanhuan;Dai Huihua;Lin Mingjuan;Wang Xiuli(Department of Obstetrics and Gynecology,the First Affiliated Hospital of NMU,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院妇产科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2019年第3期442-447,共6页Journal of Nanjing Medical University(Natural Sciences)

基　　金：2016年江苏省"333"工程项目资助(LGY2016003);2017年江苏省妇幼健康重点人才(FRC201709)

摘　　要：子宫内膜异位症是育龄期妇女最常见的妇科疾病之一。子宫内膜异位症恶变率<1%,约80%以上的子宫内膜异位症相关恶性肿瘤发生在卵巢,另外20%发生在包括肠道、直肠阴道隔、腹壁、胸膜等性腺外器官。子宫内膜异位症一旦恶变,将对患者的生命健康造成极大威胁。目前探索有效的诊断和治疗子宫内膜异位症相关恶性肿瘤的方法是临床上的主要挑战。文章针对近年来子宫内膜异位症相关恶性肿瘤的高危因素、临床病理特点、发病机制等研究进行综述。Endometriosis is a common condition in women of reproductive age. According to several epidemiological studies,endometriosis may be associated with various malignancies,but the frequency of malignancy arising in endometriosis is always supposed lower than 1%. About 80% of endometriosis-associated malignancy(EAM)have been found in the ovary,whereas 20% are localized in extragonadal sites like intestine,rectovaginal septum,abdominal wall,pleura and others. Once the endometriosis is malignant,it will pose a great threat to the health of patients. Currently,exploring effective methods for diagnosis and treatment of EAM is the major clinical challenge. The article reviews the studies of the risk factors,clinicopathological characteristics and pathogenesis of EAM.

关 键 词：子宫内膜异位症 子宫内膜异位症相关恶性肿瘤 子宫内膜异位症相关卵巢癌 

分 类 号：R711.74[医药卫生—妇产科学]