Green synthesis of gold nanoclusters using papayajuice for detection of L-lysine  

作　　者：Tian Yu Chengnan Xu Juan Qiao Rongyue Zhang Li Qi 

机构地区：[1]Beijing National Laboratory of Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Bio-systems, Institute of Chemistry, Chinese Academy of Sciences [2]Beijing Institute of Petro-chemical Technology [3]University of Chinese Academy of Sciences

出　　处：《Chinese Chemical Letters》2019年第3期660-663,共4页中国化学快报（英文版）

基　　金：financial support from the National Natural Science Foundation of China (Nos. 21575144, 91732103,21874138, 21727809, 21635008, 21621062);Chinese Academy of Sciences(No. QYZDJ-SSW-SLH034)

摘　　要：Gold nanoclusters were rapid synthesized within 3 min at 120 ℃ by using papaya juice as a capping and reducing agent(P-AuNCs). The properties of the fluorescent probe were characterized by fluorescent spectroscopy, UV-vis spectroscopy, dynamic light scattering and transmission electron microscope.Based on the surface electron density increase-induced fluorescence enhancing principle, a high selective method for detection of L-lysine was developed with the as-prepared P-AuNCs coupling the fluorescence emission at 440 nm. The fluorescent probe showed high stability and good biocompatibility. Its fluorescence intensity was found to be linearly dependent on the L-lysine concentration in the range of 10.0μmol/L to 1000.0 μmol/L(R^2=0.969) with a limit of detection of 6.0μmol/L. Furthermore, the PAuNCs based approach was applied for monitoring the urine L-lysine contents, demonstrating great potential of fluorescent probes in real samples analysis.Gold nanoclusters were rapid synthesized within 3 min at 120 ℃ by using papaya juice as a capping and reducing agent(P-AuNCs). The properties of the fluorescent probe were characterized by fluorescent spectroscopy, UV-vis spectroscopy, dynamic light scattering and transmission electron microscope.Based on the surface electron density increase-induced fluorescence enhancing principle, a high selective method for detection of L-lysine was developed with the as-prepared P-AuNCs coupling the fluorescence emission at 440 nm. The fluorescent probe showed high stability and good biocompatibility. Its fluorescence intensity was found to be linearly dependent on the L-lysine concentration in the range of 10.0μmol/L to 1000.0 μmol/L(R^2=0.969) with a limit of detection of 6.0μmol/L. Furthermore, the PAuNCs based approach was applied for monitoring the urine L-lysine contents, demonstrating great potential of fluorescent probes in real samples analysis.

关 键 词：PAPAYA juice-stabilized gold NANOCLUSTERS FLUORESCENT probe Capping agent URINE L-LYSINE 

分 类 号：O6[理学—化学]