硬脑膜修复材料的研究及应用进展  

Progress in research and application of dural substitutes for dural repair

作　　者：王位坐 敖强[2] Wang Weizuo;Ao Qiang(Department of Neurosurgery,the Fourth Affiliated Hospital of China Medical University,Shenyang 110032,China;Department of Tissue Engineering,China Medical University,Shenyang 110122,China)

机构地区：[1]中国医科大学附属第四医院神经外科,沈阳110032 [2]中国医科大学组织工程学教研室,沈阳110122

出　　处：《中华临床医师杂志（电子版）》2018年第11期639-645,共7页Chinese Journal of Clinicians(Electronic Edition)

基　　金：国家重点研发计划(2017YFA0105802);国家自然科学基金面上项目(81771351)

摘　　要：硬脑膜缺损是临床较常见的问题。目前针对硬脑膜缺损所使用的自体组织、同种异体材料、异种材料和人工合成材料等硬脑膜修补材料分别存在各自的优点与缺点;而各自的特性将影响最终的疗效。本文将综述各类硬脑膜修复材料的研究及应用进展,为优化、筛选理想的硬脑膜修复产品提供依据。Dural defect is a clinically common problem.Numerous autogenic,allogenic,xenogenic,and synthetic materials have been used to repair the dura mater in neurosurgical operations every day.There are some advantages and disadvantages for each kind of dural substitute,although they play an important role in dural repair.In this article,we review the progress in research and application of dural substitutes for dural repair,with an aim to guide the choice of ideal dural substitutes in clinical applications.

关 键 词：硬脑膜缺损 修复重建 材料 代谢 神经外科 组织工程 

分 类 号：R651[医药卫生—外科学]