Preparation of a New Friedlander Synthon, 2,3‐Diaminobenzene‐1,4‐dicarbaldehyde, and Its Application towards Synthesis of 1,10‐Phenanthrolines and Related Cyclophane  

作　　者：Yang Lu Yurngdong Jahng 

机构地区：[1]College of Pharmacy,Yeungnam University,Gyeongsan 38541,Korea

出　　处：《Chinese Journal of Chemistry》2019年第3期221-225,共5页中国化学（英文版）

摘　　要：Summary of main observation and conclusion A new Friedlander synthon, 2,3‐diaminobenzene‐1,4‐dicarbaldehyde, was prepared from p‐xylene in 4 steps, of which the Friedlander reaction with acetaldehyde and acetone in a Schulenk bottle afforded 1,10‐phenathroline and neocuprine in 44% and 82% yield, respectively. The scope of the Friedlander reactions of 2,3‐diaminobenzene‐1,4‐dicarbaldehyde, including the synthesis of hexaazacyclic cyclophane with 1,10‐phenanthroline and pyridine units, was described.

关 键 词：ITS SCOPE was 

分 类 号：U491[交通运输工程—交通运输规划与管理]