Revolution CT单能量成像在不同浓度对比剂中对冠状动脉斑块检出价值的体模研究  

The value of monochromatic energy imaging derived from Revolution CT in detecting coronary plaques with different concentration of contrast agent: a phantom experiment

作　　者：李伟然 吕培杰[1] 赵慧萍[1] 李莹[1] 王会霞 高剑波[1] LI Weiran;Lv Peijie;ZHAO Huiping;LI Ying;WANG Huixia;GAO Jianbo(Department of Radiology 9the First Affiliated Hospital of Zhengzhou University ,Zhengzhou 450052 ,China)

机构地区：[1]郑州大学第一附属医院放射科,河南郑州450052

出　　处：《实用放射学杂志》2019年第4期647-650,654,共5页Journal of Practical Radiology

基　　金：国家门然科学慕金青年基金项目(81301220);河南省佞学科技攻关计划普通项目(201403016);郑州大学第一附属原院青年创新基金项忖(2012-233)。

摘　　要：目的探讨RevolutionCT单能量成像在不同浓度对比剂中检出冠状动脉斑块的价值。方法选取的体模有编号为3、4、5、6、8.9的6支试管,分别含有20、10、5、2.5、0、13mgI/mL等不同浓度的碘溶液,每支试管内放有模拟钙化斑块的鱼刺和模拟脂质斑块及纤维斑块的五花肉;分别对体模进行能谱及120kVp扫描.获得试验组70keV单能量图像及对照组120kVp图像;对2组图像斑块检出能力进行主观评分,对评分Z3分的图像进一步分析.组内不同试管同性质斑块CT值及CNR比较采用单因素方差分析,组内两两比较采用l^nferrom法.组间同号试管同性质斑块的CT值、CNR及组间标准差(SD)值比较采用配对t检验或符号秩和检验。结果试验组及对照组4号、5号及9号试管各斑块的主观评分均符合诊断要求;组内比较显示,试验组及对照组5号试管钙化斑块CNR、9号试管脂质斑块及纤维斑块CNR高于其余试管同性质斑块,差异有统计学意义(t=4.105.29.214,均P<0.001);组间比较显示,9号试管钙化斑块CNR差异无统计学意义(t=—1.576,p=0.130).余各斑块CNR均为试验组高于对照组(Z=—4.074^-3.815,t=-14.782^-3.520,均PV0.05)。结论RevolutionCT能谱单能量成像能够获得优质的图像,在5~13mgI/mL对比剂条件下较好地显示冠状动脉斑块。Objective To explore the value of monochromatic en ergy imaging gen era ted from Revoluti on CT in detecting cor on ary plaques in different concentrations of contrast agent.Methods Six test tubes numbered 3, 4, 5, 6, 8 and 9 in the phantom were selected and filled up with different concentrations of iodine solutions)20, 10, 5 , 2.5 , 0, 13 mg 1/mL, respectively), fishbone simulating calcified plaque and streaky pork simulating lipid/fibrous plaque. Each tube underwent spectral CT scan(study group,70 keV monochromatic energy imaging) and 120 kVp CT scan ( control group) respectively in Revolution CT. The ability of plaque detection was evaluated subjectively, and further analysis was made on the images with a score greater than or equal to three points.One-way ANOVA and Borjferroni method were used to compare the CT values and NR in different tubes in the intra-group comparison, while paired t test and Mann- Whitney U test were used for the inter-group comparison. Results The overall image quality of No.4 , 5 and 9 test tubes in both groups met the clinical diagnostic level. In the intra-group comparison, No.5 test tube showed higher CNR of calcified plaque and No.9 test tube showed higher CNR of lipid plaque and fibrous plaque than the others (t=4.105 -29.21 1,all PV0.001).While in the intergroup comparison, the study group showed similar CNR of calcified plaque in No.9 test tube(t =- 1.576,P =0.130) to the control group, and higher CNR in the others than the control group(Z =-4.074--3.815 , t=- 14.782--3.520, all P <0.05).Conclusion Compared with 120 kVp CT images, monochromatic energy imaging at 70 keV from Revolution CT showed better overall image quality “nd could display coronary plaques better with the contrast agent concentration from 5 mg I/mL to 13 mg I/mL.

关 键 词：单能量成像 体模 斑块 对比剂 

分 类 号：R814.42[医药卫生—影像医学与核医学] R331[医药卫生—放射医学]