中药类保健食品增强免疫力功能评价现状和研究策略  

Current evaluation situation and research strategies on enhanced immune function of health food containing Chinese materia medica

作　　者：齐晓甜 赵春媛 张家祥 黄娜娜 张贵民 李晓宇[3,6] 孙蓉[1,4] QI Xiao-tian;ZHAO Chun-yuan;ZHANG Jia-xiang;HUANG Na-na;ZHANG Gui-min;LI Xiao-yu;SUN Rong(School of Advanced Medical Science,Shandong University,Jinan 250012,China;School of Basic Medical Science,Shandong University,Jinan 250012,China;The Second Hospital of Shandong University,Jinan 250033,China;Shandong University of Traditional Chinese Medicine,Jinan 250355 ,China;State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine,Lunan Pharmaceutical Group,Linyi 276000,China;Shandong Academy of Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东大学高等医学研究院,山东济南250012 [2]山东大学基础医学院,山东济南250012 [3]山东中医药大学,山东济南250355 [4]山东大学第二医院,山东济南250033 [5]鲁南制药集团股份有限公司中药制药共性技术国家重点实验室,山东临沂276000 [6]山东省中医药研究院,山东济南250014

出　　处：《中国中药杂志》2019年第5期875-879,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金面上项目(81773997);中国博士后科学基金面上项目(2018M640642);山东省重点研发计划项目(2016ZDJS07A21;2017CXGC1301);山东省自主创新和成果转化课题(2014ZZCX02104);泰山学者工程专项经费项目(Ns201511107)

摘　　要：目前中药类复方保健食品的保健功能评价缺乏中医药理论支持,不能充分体现保健功能的作用特征、量效关系、作用机制,保健食品评价技术规范相对滞后,且已废除。增强免疫功能的中药复方保健食品在已批复的产品中占比最高,已高达30. 33%。该文对中药保健食品增强免疫功能评价现状进行归纳、分析和挖掘,发现目前中药保健食品的评价与其他保健食品的评价未进行区分,缺乏中医药特色。中药保健食品增强免疫力功能的评价不仅缺乏中医理论指导,而且技术手段滞后,缺乏免疫活性物质相关评价的技术手段,免疫细胞评价部分亟待细化完善,限制了中药保健食品行业的发展。因此,中药保健食品的增强免疫功能评价应以中医药养生理论为指导,中医体质辨识为基础,紧密围绕其保健功能声称,结合现代科学技术手段,提出新的评价模式,制订适宜于评价中药保健食品保健功能作用的评价技术和技术规范,从根本上保证中药保健食品产业的健康、有序、快速、持续发展。At present,the function evaluation of health food containing Chinese materia medica is in lack of theoretical support of Chinese medicine,which can’t reflect the function characteristics,dose-effect relationship and mechanism of functional food. What’ s more,the evaluation technology of health food containing Chinese materia medica is relatively lagging behind and has been abolished now,which seriously restricts the development of health food containing Chinese materia medica industry. The proportion of health food containing Chinese materia medica with enhancing immune function is the highest among approved products,which is up to 30.33%. By collecting,analyzing and digging the current evaluation situation of enhancing immune function of health food containing Chinese materia medica,this paper has shown that there is no difference between health food containing Chinese materia medica evaluation and other functional food evaluation. What’s more,there is a lack of characteristics of traditional Chinese medicine(TCM). The technological means including evaluation of immune active substances is under-developed and the immune cell evaluation needs to be refined and improved urgently,restricting the development of health food containing Chinese materia medica industry. Therefore,the evaluation of the enhanced immune function of health food containing Chinese materia medica should be guided by health-preserving theory in TCM,and based on the identification of TCM constitution for its claim of health function. With TCM theory and modern scientific technological means,a new evaluation model for immune function enhancement of health food containing Chinese materia medica is put forward to distinguish it from other functional food and traditional medicines. Formulation of the evaluation technology and technical specifications suitable for health food containing Chinese materia medica can fundamentally ensure the healthy,orderly,fast and sustainable development of health food containing Chinese materia medica industry.

关 键 词：中药保健食品 免疫功能 中性粒细胞 中医体质辨识 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]