用浓度为1%的盐酸布替萘芬乳膏治疗花斑癣的效果研析  

Effect of concentration 1% of Butenafine Hydrochloride Cream for tinea versicolor

作　　者：付静 Fu Jing(Jianyang hospital of traditional Chinese medicine,Jianyang Sichuan 641400)

机构地区：[1]简阳市中医院,四川简阳641400

出　　处：《当代医药论丛》2019年第5期26-27,共2页

摘　　要：目的:探讨用浓度为1%的盐酸布替萘芬乳膏治疗花斑癣的临床效果。方法:将2017年2月至2018年2月期间简阳市中医院收治的88例花斑癣患者作为研究对象,并将其分为对照组(n=42)和试验组(n=46)。为对照组患者使用硝酸益康唑软膏进行治疗,为试验组患者使用浓度为1%的盐酸布替萘芬乳膏进行治疗。然后,比较两组患者治疗前后其临床症状的评分和DLQI的评分、临床疗效、不良反应的发生率。结果:治疗后,与对照组患者相比,试验组患者单项症状的评分和总评分均更低,其DLQI的评分、治疗的总有效率均更高(P <0.05)。两组患者不良反应的发生率相比,差异无统计学意义(P>0.05)。结论:用浓度为1%的盐酸布替萘芬乳膏治疗花斑癣的效果确切,可有效地改善患者的临床症状,降低其不良反应的发生率,提高其生活质量。objective:to investigate the clinical effect of butenafine hydrochloride cream with a concentration of 1%in the treatment of tinea versicolor.Methods:88 patients with tinea versicolor admitted to jianyang hospital of traditional Chinese medicine from February 2017 to February 2018 were selected as study subjects and divided into control group(n=42)and experimental group(n=46).Patients in the control group were treated with yiconazole nitrate ointment,and patients in the experimental group were treated with butenafine hydrochloride cream with a concentration of 1%.Then,the scores of clinical symptoms and DLQI,clinical efficacy and the incidence of adverse reactions were compared between the two groups before and after treatment.Results:after treatment,compared with patients in the control group,patients in the test group had lower scores of single symptom and total score,and their DLQI scores and total effective rate of treatment were higher(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:butenafine hydrochloride cream with concentration of 1%is effective in the treatment of tinea versicolor,which can effectively improve the clinical symptoms,reduce the incidence of adverse reactions and improve the quality of life.

关 键 词：花斑癣 盐酸布替萘芬乳膏 硝酸益康唑软膏 

分 类 号：R756[医药卫生—皮肤病学与性病学]