参麦注射液对急性心肌梗死的疗效及对患者心功能的影响  

Effect of Shenmai injection on cardiac function in patients with acute myocardial infarction

作　　者：饶堃睿 杨俊 虞佳[1] 郑春华[1] Rao Kunrui;Yang Jun;Yu Jia;Zheng Chunhua(Nanchang First Hospital, Nanchang, Jiangxi, 330000, China)

机构地区：[1]南昌市第一医院,江西南昌330000

出　　处：《当代医学》2019年第14期62-64,共3页Contemporary Medicine

摘　　要：目的探讨参麦注射液对急性心肌梗死的疗效及对患者BNP、cTnT和心功能的影响。方法 80例急性心肌梗死患者随机分为对照组和研究组(参照随机数字表法分组),每组40例。对照组患者予以基础常规治疗,研究组患者在对照组基础上联合参麦注射液进行治疗。观察患者住院治疗后的临床疗效情况;观察比较两组患者治疗前后BNP(脑钠肽)、cTnT(肌钙蛋白T)水平变化情况及心功能指标变化情况,并用统计学软件进行数据分析。结果治疗后,研究组临床总有效率是90.0%,高于对照组的77.5%,差异有统计学意义(P<0.05);两组患者经治疗后BNP、cTnT水平均明显下降,且研究组下降程度更明显,差异有统计学意义(P<0.05);两组患者经治疗后心功能均明显改善,研究组心功能评价指标优于对照组,两组比较差异有统计学意义(P<0.05)。结论对急性心肌梗死患者应用参麦注射液联合基础常规治疗,可促进患者BNP、cTnT水平下降,有效改善患者心肌功能,有实用临床价值。Objective To investigate the effect of Shenmai injection on BNP, cTnT and cardiac function in patients with acute myocardial infarction(AMI). Methods Eighty patients with acute myocardial infarction were randomly divided into two groups: control group(n=40) and study group(n=40). The patients in the control group were treated with basic routine therapy, and the patients in the study group were treated with Shenmai injection on the basis of the control group.The changes of BNP, cTnT and cardiac function indexes before and after treatment between the two groups were observed, and the data were analyzed by statistical software. Results After treatment, the total clinical effective rate of the study group was 90.0%, which was higher than the control group(77.5%), the difference was statistically significant(P<0.05). After treatment, the level of BNP,cTnT in the two groups decreased significantly, and the degree of decrease in the study group was more obvious, the difference was statistically significant(P<0. 05). The cardiac function of the study group was better than control group, and there was a significant difference between the two groups(P<0.05). Conclusion The application of Shenmai injection combined with basic routine therapy in patients with acute myocardial infarction can promote the decrease of BNP, cTnT level and effectively improve the myocardial function of the patients, which is of practical clinical value.

关 键 词：急性心肌梗死 脑钠肽 肌钙蛋白T 参麦注射液 心功能 

分 类 号：R542.22[医药卫生—心血管疾病]