冠心病伴抗着丝点抗体强阳性一例报道  

Coronary Heart Disease Accompanied with Strongly Positive Anti-centromere Antibody:a Case Report

作　　者：孙兆庆 闫波[2] SUN Zhaoqing;YAN Bo(Qilu Medical College of Shandong University,Jinan 250012,China;The Affiliated Hospital of Jining Medical College,Jining 272029,China)

机构地区：[1]山东大学齐鲁医学院,山东省济南市250012 [2]济宁医学院附属医院,山东省济宁市272029

出　　处：《实用心脑肺血管病杂志》2019年第3期115-117,120,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：近年研究表明,自身免疫疾病在冠心病的发生发展过程中具有一定作用,但冠心病合并自身免疫疾病的病例报告非常少见。本文报道了1例冠心病伴抗着丝点抗体强阳性患者,提示临床医生接诊常见冠心病危险因素不典型但冠状动脉狭窄程度却呈进行性加重的患者时应警惕自身免疫疾病的存在,应注意结合患者临床表现及病史完善自身抗体检查,尽早明确诊断并指导临床制定合理的治疗方案,以改善患者预后。Recent studies showed that,autoimmune disease play a role in the occurrence and development of coronary heart disease,but case reports about coronary heart disease merged with autoimmune disease is relatively rare.This paper reported a coronary heart disease patient accompanied with strongly positive anti-centromere antibody,reminding that clinicians should be aware of autoimmune disease when found progressive aggravation of coronary artery stenosis without atypical common risk factors of coronary heart disease,which need perfect the autoantibody test according to the clinical manifestation and medical history,to clarify the diagnosis as early as possible,thus to guide the clinical reasonable treatment plan and improve the prognosis.

关 键 词：冠心病 动脉粥样硬化 自身免疫疾病 抗着丝点抗体 病例报告 

分 类 号：R541.4[医药卫生—心血管疾病] R593.2[医药卫生—内科学]