干细胞治疗宫腔粘连的研究进展  

Research progress of stem cell based therapy for intrauterine adhesion

作　　者：郭灵 邵晓雯[2] 成佳景 GUO Ling;SHAO Xiao-wen;CHENG Jia-jing(Tenth People's Hospital,Clinical Medical College of Nanjing Medical University,Nanjing 211166,China;Dept.of Obsterics and Gynecology,Tenth People's Hospital,Tongji University,Shanghai 200072,China)

机构地区：[1]南京医科大学上海十院临床医学院,南京211166 [2]同济大学附属第十人民医院妇产科,上海200072

出　　处：《同济大学学报（医学版）》2019年第2期254-259,共6页Journal of Tongji University(Medical Science)

基　　金：中央高校交叉学科重大项目(1500219107)

摘　　要：宫腔粘连已成为女性继发不孕的重要病因之一。传统的治疗方法 ,激素联合手术治疗,是目前治疗宫腔黏连的主要方法 ,但疗效不佳。这主要是由于子宫内膜基底层受损,导致再生障碍。近年来,干细胞技术的应用,使子宫内膜基底层的修复及子宫内膜再生成为可能,为宫腔粘连的治疗带来新的希望。Intrauterine adhesion is one of the most important causes leading to subsequent infertility in women.The conventional estrogen therapy combined with surgery is now the main treatment for intrauterine adhesion.However,the efficacy has been not satisfactory,mainly due to the damage of endometrial basal layer.In recent years,the application of stem cells makes restoration of endometrial basal layer and regeneration of endometrium possible,which brings new hope for therapy of intrauterine adhesion.

关 键 词：宫腔粘连 子宫内膜 干细胞 治疗 

分 类 号：R711.32[医药卫生—妇产科学]