某院多囊卵巢综合征患者的用药情况分析  

Drug use in patients with polycystic ovary syndrome at some hospital

作　　者：赵晶晶[1] 阳巧凤[1] 朱文思 毕婷婷[1] Zhao Jingjing;Yang Qiaofeng;Zhu Wensi;Bi Tingting(Department of Pharmacy, GuangDong Women and Children Hospital, Guangzhou 511442, China)

机构地区：[1]广东省妇幼保健院药学部,广州511442

出　　处：《国际医药卫生导报》2019年第7期1064-1067,共4页International Medicine and Health Guidance News

摘　　要：目的通过对本院门诊多囊卵巢综合征(PCOS)用药情况进行统计分析,为改善治疗方案,推进临床合理用药提供参考.方法收集本院2017年6月至12月治疗PCOS的门诊处方,采用相关软件对收集的处方进行分析,计算出药物销售金额排序、用药频度(DDDs)等数据,并评估用药合理性.结果在统计的1 373张处方中,26~30岁年龄段的就诊患者较多,占总就诊数的46.76%.用药频度较高的药物分别是:炔雌醇环丙孕酮片(29.86%)、戊酸雌二醇片(17.92%)、黄体酮胶丸(软胶囊)(17.26%)、二甲双胍肠溶片(14.64%)、尿促性素冻干粉针(12.75%).联合用药占所有处方中的60.96%,其中二联占联合用药处方的40.13%.结论本院门诊多囊卵巢综合征用药基本合理,主要以激素相关类药物为主,联合中成药等其他药物以达到预防和治疗疾病的效果.Objective To provide some references for optimizing the treatment plans and improving the rational drug use in clinic investigating the drug application in outpatients with polycystic ovary syndrome (PCOS).Methods The data of prescriptions for the outpatients with PCOS treated at our hospital from June to December,2017 were collected,sorted,and analyzed by Excel software.The DDDs and DDC were calculated;and the medication rationality was evaluated.Results Among the 1 373 prescriptions,the age of most the outpatients ranged from 26 to 30,which accounted for 46.76%.The top 5 therapeutic drugs in the respect of DDDs were ethinylestradione tablet (29.86%),estradiol valerate (17.92%),progesterone capsules (17.26%),metformin entericcoated tablets (14.64%),and lyophilized powder (12.75%).The combination therapy accounted for 60.96% of all the prescriptions,in which the two-drug combination accounted for 40.13%.Conclusions The drug application for outpatients with PCOS at our hospital is basically reasonable.At present,our hospital mainly applies the hormone-related drugs,and combines with Chinese medicine and other adjuvant drugs to achieve the treatment and prevention of the disease.

关 键 词：多囊卵巢综合征 用药情况分析 合理用药 

分 类 号：R711.75[医药卫生—妇产科学]