"阴腹联合"腹腔镜阴道骶骨固定术治疗Ⅳ度盆腔器官脱垂的中期疗效  

Mid-term efficacy of laparoscopic sacral colpopexy of combined transabdominal-transvaginal approach in the treatment of stage Ⅳ pelvic organ prolapse

作　　者：梁雪早 徐丽珍[1] 陈礼全[1] 王苏[1] 林晓婷 张晓薇[1] Liang Xuezao;Xu Lizhen;Chen Liquan;Wang Su;Lin Xiaoting;Zhang Xiaowei(Department of Obstetrics and Gynecology, First Affiliated Hospital of Guangzhou Medical University. Guangzhou 510120,China)

机构地区：[1]广州医科大学附属第一医院妇产科,510120

出　　处：《中华妇产科杂志》2019年第3期160-165,共6页Chinese Journal of Obstetrics and Gynecology

基　　金：广东省产业技术研究与开发资金计划(2011B010200044)。

摘　　要：目的探讨"阴腹联合"腹腔镜阴道骶骨固定术治疗Ⅳ度盆腔器官脱垂的中期疗效。方法回顾性分析2010年1月1日至2017年7月30日因Ⅳ度盆腔器官脱垂在广州医科大学附属第一医院行"阴腹联合"腹腔镜阴道骶骨固定术患者65例的临床资料。通过比较术前、术后盆腔器官脱垂定量(POP-Q)分度法的各指示点位置评估客观疗效,以盆底不适调查表简表(PFDI-20)、盆底功能影响问卷简表(PFIQ-7)、盆底器官脱垂与尿失禁性功能问卷(PISQ-12)、患者整体印象改善评分(PGI-I)评估主观疗效。采用门诊和电话的方式随访。结果65例患者均顺利完成手术,无术中并发症,术中出血量20~250 ml,术后留置尿管天数为(2.5±1.1)d,术后住院天数为(6.2±1.7)d。门诊随访53例,电话随访12例,随访时间为6.1~80.3个月,中位随访时间为24.5个月。术前、术后POP-Q指示点(Aa、Ba、C、TVL、Ap、Bp、gh)的位置分别比较,差异均有统计学意义(P均<0.01)。阴道前壁、阴道顶端及阴道后壁脱垂Ⅳ度的客观治愈率分别为90%(47/52)、100%(23/23)和95%(20/21)。PGI-I评分除1例患者为"有改善"外,其余64例(98%,64/65)均为"明显改善";65例患者术前、术后的PFDI-20、PFIQ-7、PISQ-12评分分别比较,差异均有统计学意义(P均<0.01),主观疗效显著。术后并发症:术后病率5%(3/65);网片暴露2例(4%,2/53),其中1例为阴道顶端网片暴露、1例为阴道前壁网片暴露。术后复发:6例患者(11%,6/53)术后脱垂复发,其中5例为阴道前壁脱垂复发,均为POP-QⅡ度,无脱垂相关症状,均未再次手术;1例为阴道后壁脱垂复发,诊断为阴道后壁脱垂Ⅲ度。无阴道顶端脱垂复发。再次手术率(包括暴露网片清除术2例及后盆腔重建术1例)为5%(3/65)。结论"阴腹联合"腹腔镜阴道骶骨固定术对于Ⅳ度盆腔器官脱垂患者的主观治愈率高,阴道顶端脱垂的客观治愈率也高,网片暴露率低,再次手术率低,术后感染率低,�Objective To evaluate the clinical effect after laparoscopic sacral colpopexy (LSC) of combined transabdominal-transvaginal approach on stage Ⅳ pelvic organs prolapse (POP). Methods The clinical data of 65 patients undergoing LSC of combined transabdominal-transvaginal approach from January 1st, 2010 to July 30th, 2017 due to POP stage Ⅳ in First Affiliated Hospital of Guangzhou Medical University were retrospectively analyzed. Objective outcome was assessed by comparing preoperative and postoperative pelvic organ prolapse quantification (POP-Q) systems. Subjective effects were assessed by comparing pelvic floor distress inventory-short form 20 (PFDI-20), pelvic floor impact questionnaire short form (PFIQ-7), pelvic organ prolapse/urinary incontinence sexual questionnaire-12 (PISQ-12) and patient global impression of improvement (PGI-I). Results All 65 patients were successfully performed without any intraoperative complications. Fifty-three patients were followed in the clinic department and 12 were followed up by telephone. The follow-up duration was 6.1-80.3 months and the median follow-up duration was 24.5 months. The bleeding loss was 20-250 ml. Postoperative urethral catheter residence day was (2.5±1.1) days, length of postoperative stay was (6.2±1.7) days. The postoperative POP-Q scores were compared with preoperative scores which had significantly improved except pb (all P<0.01). The objective cure rates of vaginal anterior wall, apical and posterior wall prolapse stage Ⅳ were 90%(47/52), 100%(23/23) and 95%(20/21).About PGI-I, except for 1 patient who chose "improvement", the other 64 patients (98%, 64/65) all chose "significant improvement". Furthermore, preoperative and postoperative PFDI-20, PFIQ-7, and PISQ-12 scores were all statistically significant (all P<0.01). Subjective efficacy was significant. Three cases (5%, 3/65) of postoperative fever occurred. Two cases (4%, 2/53) had mesh exposure. Six patients (11%, 6/53) had recurrence of postoperative prolapse. Five cases had recurrence of va

关 键 词：盆腔器官脱垂 妇科外科手术 腹腔镜检査 复发 阴道 紙骨 

分 类 号：R713[医药卫生—妇产科学]