血管内超声引导药物洗脱支架植入治疗冠状动脉慢性闭塞病变远期疗效的探讨  

Long-term Effect of Intravascular Ultrasound Guided Drug-eluting Stent Implantation in the Treatment of Chronic Coronary Occlusive Disease

作　　者：肖丽梅[1] 谷青[1] 胡国春[1] XIAO Li-mei;GU Qing;HU Guo-chun(Department of Cardiology, Yuxi People's Hospital, Yuxi, Yunnan Province, 653100 China)

机构地区：[1]玉溪市人民医院心内科,云南玉溪653100

出　　处：《中外医疗》2019年第8期60-62,共3页China & Foreign Medical Treatment

摘　　要：目的探讨对冠状动脉慢性闭塞病变患者分别选择IVUS(血管内超声)引导DES(药物洗脱支架植入)方法以及CAG(冠状动脉造影)引导DES(药物洗脱支架植入)方法治疗后获得的临床效果。方法方便选择该院2016年6月—2018年3月收治的62例冠状动脉慢性闭塞病变患者作为实验对象;采用抽签法分组后进行冠状动脉慢性闭塞病变患者手术方式的选择;对照组(31例):选择CAG引导DES方法展开治疗;观察组(31例):选择IVUS引导DES方法展开治疗;最终就两组冠状动脉慢性闭塞病变患者支架后即刻RVD、造影随访时RVD、支架后即刻MLD、造影随访时MLD、LLL水平、CTO支架直径、CTO支架直径长度、X线曝光时间、对比剂用量以及手术时间展开对比。结果观察组支架后即刻RVD(2.96±0.47)mm、造影随访时RVD(2.97±0.49)mm、支架后即刻MLD(2.63±0.46)mm、造影随访时MLD(2.37±0.72)mm、LLL水平(0.29±0.09)、CTO支架直径(3.06±0.49)mm;对照组支架后即刻RVD(2.59±0.43)mm、造影随访时RVD(2.32±0.43)mm、支架后即刻MLD(2.21±0.49)mm、造影随访时MLD(1.98±0.75)mm、LLL水平(0.45±0.09)、CTO支架直径(2.57±0.38)mm;同对照组冠状动脉慢性闭塞病变患者支架后即刻RVD、造影随访时RVD、支架后即刻MLD、造影随访时MLD以及LLL水平展开对比,观察组获得明显改善(t=3.233 8,5.551 3,3.479 4,8.836 3,6.999 1,P<0.05);观察组CTO支架直径长度为(54.29±22.25)mm、X线曝光时间(77.15±60.25)min、对比剂用量为(292.55±140.13)mL、手术时间为(85.25±48.13)min;对照组CTO支架直径长度为(51.35±24.22)mm、X线曝光时间(72.29±60.33)min、对比剂用量为(292.92±136.55)mL、手术时间为(89.29±55.39)min;同对照组冠状动脉慢性闭塞病变患者CTO支架直径展开对比,观察组获得明显改善(t=4.399 7,P<0.05)。同对照组冠状动脉慢性闭塞病变患者CTO支架直径长度、X线曝光时间、对比剂用量以及手术时间展开对比,观察组差异无统Objective To investigate the choice of IVUS (intravascular ultrasound) guided DES (drug-eluting stent implan-tation) and CAG (coronary angiography) guided DES (drug-eluting stent implantation) in patients with chronic coronary oc-clusion disease, and then the clinical effect was obtained. Methods 62 patients with chronic coronary occlusive disease ad-mitted to our hospital from June 2016 to March 2018 were selected as subjects. The surgical methods for patients with chronic coronary occlusion disease were selected by grouping. The control group (31 cases): CAG guided DES method was used for treatment;observation group (31 cases): IVUS guided DES method was selected for treatment;finally, two groups of patients with chronic coronary occlusion disease immediately after stenting RVD, RVD after angiographic follow-up, MLD immediately after stent, MLD, LLL level, CTO stent diameter, CTO stent diameter length, X-ray exposure time, contrast a-gent dosage and operation time were compared during angiographic follow-up. Results RVD (2.96±0.47) mm immediately after stenting, RVD (2.97±0.49) mm at angiographic follow-up, MLD (2.63±0.46) mm immediately after stenting, MLD (2.37 ±0.72) mm, LLL level at angiographic follow -up (0.29±0.09), CTO stent diameter (3.06±0.49) mm;RVD (2.59±0.43) mm immediately after stent implantation, RVD (2.32±0.43) mm at angiographic follow-up, and MLD (2.21±0.49) mm immediately after stent implantation MLD (1.98±0.75) mm, LLL level (0.45±0.09), CTO stent diameter (2.57±0.38) mm during angiographic follow-up;RVD immediately after stenting in patients with chronic occlusive disease of coronary artery, RVD during angiographic follow-up immediately after MLD, MLD and LLL levels were compared, the observation group was significantly improved (P<0.05, t=3.2338, 5.5513, 3.4794, 8.8363, 6.9991);the length of the CTO stent in the observation group was (54.29±22.25) mm, X-ray exposure time (77.15±60.25) min, contrast agent dosage (292.55±140.13) mL, operation time (85.25±48.13) min;control g

关 键 词：血管内超声引导 CAG引导DES IVUS引导DES 临床效果 

分 类 号：R543[医药卫生—心血管疾病]