导管溶栓联合压力治疗系统在急性下肢深静脉血栓形成中的应用效果分析  

Application of catheter thrombolysis combined with pressure therapy system in acute deep venous thrombosis of lower extremities

作　　者：王晓雨 张磊[1] 吴常生[1] 闫瑞强[1] 刘海艳[1] 穆永旭[1] Wang Xiaoyu;Zhang Lei;Wu Changsheng;Yan Ruiqiang;Liu Haiyan;Mu Yongxu(Department of Interventional Therapy, the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014010, China;Graduate School of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014010, China.)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院介入治疗科,内蒙古包头014010 [2]内蒙古科技大学包头医学院研究生院,内蒙古包头014010

出　　处：《中华介入放射学电子杂志》2019年第2期147-150,共4页Chinese Journal of Interventional Radiology：electronic edition

摘　　要：目的:研究导管溶栓联合压力治疗系统治疗急性下肢深静脉血栓(LEDVT)形成的临床效果及其并发症。方法:选取内蒙古科技大学包头医学院第一附属医院2016年1月至2018年1月收治的急性LEDVT患者66例。随机数字表法分为观察组及对照组,每组33例。对照组入院后给予抗凝、下腔静脉滤器置入、导管溶栓等常规治疗,观察组在对照组的治疗基础上采用空气波压力治疗系统进行压力治疗。结果:治疗前,两组的大腿周径[(55.90±4.51) cm vs.(54.10±5.04) cm]和小腿周径[(44.72±3.45) cm vs.(42.85±6.53) cm]差异无统计学意义;治疗后,观察组大腿周径[(44.90±1.99) cm vs.(47.25±4.08) cm]和小腿周径[(34.25±1.51) cm vs.(37.45±1.84) cm]均明显小于对照组,差异均有统计学意义(P<0.05)。治疗后1周,观察组的患肢皮肤温度、皮肤色泽、疼痛和通畅度评分均明显低于对照组,差异有统计学意义(P<0.05)。两组患者均出现了溶栓并发症,观察组总发生率为15.15%(5/33),对照组总发生率为12.12%(4/33),差异无统计学意义(χ^2=0.129,P=0.720);两组均未出现便血、死亡等严重并发症。结论:导管溶栓联合压力治疗LEDVT较单纯导管溶栓可以明显提高疗效、缩短疗程、减轻患者患肢症状。为LEDVT的治疗提供了全新、有效、可行的治疗方法,值得临床推广使用。Objective: To investigate the clinical effect and complications of catheter thrombolysis combined with pressure therapy system in the treatment of acute deep venous thrombosis of lower extremiti(LEDVT). Methods: Totally 66 patients with acute LEDVT in the First Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology from January 2016 to January 2018 were selected. The patients were divided into observation group and control group using random number table method, 33 cases in each group. The patients in control group were treated with anticoagulation, inferior vena cava filter implantation and catheter thrombolysis after admission, while the patients in observation group were treated with air wave pressure treatment system. Results: Before treatment, there was no significant difference in thigh circumference[(55.90±4.51) cm vs.(54.10±5.04) cm] and leg circumference [(44.72±3.45) cm vs.(42.85±6.53) cm] between the two groups. After treatment, thigh circumference [(44.90±1.99) cm vs.(47.25±4.08) cm] and leg circumference[(34.25±1.51) cm vs.(37.45±1.84) cm) in the observation group were significantly smaller than those in the control group, with significant difference(P<0.05). One week after treatment, the skin temperature, skin color, pain and patency scores of the affected limbs in the observation group were significantly lower than those in the control group(P<0.05). The total incidence of thrombolytic complications was 15.15%(5/33) in the observation group and 12.12%(4/33) in the control group. There was no significant difference between the two groups(χ^2=0.129, P=0.720). Conclusions: Compared with catheter thrombolysis alone, catheter thrombolysis combined with pressure therapy for LEDVT can significantly improve the curative effect, shorten the course of treatment and alleviate limb symptoms. It provides a new, effective and feasible method for the treatment of LEDVT, which is worthy of clinical application.

关 键 词：静脉血栓形成 导管溶栓 压力治疗系统 机械溶栓 

分 类 号：R654.4[医药卫生—外科学]