冬病夏治穴位贴敷预防支气管哮喘急性发作的临床研究  

Clinical study on prevention of bronchial asthma attack by acupoint application of "winter disease cured in summer"

作　　者：杨成武 钟树志[2] 杨骏[3] 袁爱红[4] 吴安源 YANG Chengwu;ZHONG Shuzhi;YANG Jun(The Eighth People's Hospital of Hefei, Anhui 238000)

机构地区：[1]安徽省合肥市第八人民医院中医科,安徽合肥238000 [2]皖南医学院组织与胚胎学教研室,安徽芜湖241000 [3]安徽中医药大学第一附属医院,安徽合肥230000 [4]安徽中医药大学第一附属医院针推科,安徽合肥230000

出　　处：《河北中医》2019年第3期434-438,共5页Hebei Journal of Traditional Chinese Medicine

基　　金："十二五"国家科技支撑计划(编号:2015BAI04B11)

摘　　要：目的观察冬病夏治穴位贴敷预防支气管哮喘(以下简称哮喘)急性发作的临床疗效。方法将40例哮喘非急性发作期患者按照随机数字表法分为2组。试验组21例第1年采用1号药膏治疗,第2、3年采用2号药膏治疗;对照组19例3年均采用1号药膏治疗。2组均于2015、2016、2017年的头伏、二伏、三伏的第1 d各贴敷1次。2组每年治疗结束后均于次年头伏第1 d治疗前随访1次,采用哮喘控制测试(ACT)评价3年哮喘控制情况,比较2组3年肺功能指标[第1 s用力呼气容积占预计值百分比(FEV_1%)、第1 s用力呼气容积占用力肺活量百分比(FEV_1/FVC)、呼气峰值流速(PEF)]及哮喘急性发作次数,并观察穴位贴敷治疗期间皮肤反应。结果 2组随访时哮喘控制率逐年升高,其中试验组第3次随访控制率高于第1次随访(P<0.05);试验组第3次随访时哮喘控制率高于对照组(P<0.05)。2组第1、2、3次随访时FEV_1%、FEV_1/FVC、PEF较本组治疗前均升高(P<0.05),第2、3次随访时FEV_1%、FEV_1/FVC、PEF均高于第1次随访(P<0.05);试验组第3次随访时FEV_1%、FEV_1/FVC、PEF均高于第2次随访(P<0.05)。试验组第2、3次随访时FEV_1%、FEV_1/FVC、PEF均高于对照组(P<0.05)。2组第2、3次随访时急性发作次数均低于第1次随访(P<0.05),第3次随访时急性发作次数低于第2次随访(P<0.05)。2组第1次随访时急性发作次数比较差异无统计学意义(P>0.05),第2、3次随访时试验组急性发作次数低于对照组(P<0.05)。2组第1、2、3年皮肤红斑、水疱评分比较差异无统计学意义(P>0.05)。结论冬病夏治穴位贴敷可改善非急性发作期哮喘患者肺功能,减少每年急性发作次数,随着贴敷药物剂量增加效果更加显著,且不会加重皮肤刺激反应,安全性较高。Objective To observe the clinical effects of acupoint application of "winter disease cured in summer" on prevention attack of bronchial asthma (hereinafter referred to as asthma). Methods 40 patients with non-acute asthma attack were divided into two groups according to random number table method. 21 cases in experimental group were treated by No. 1 ointment in the first year and No. 2 ointment in the second and third years. 19 cases in control group were treated by No. 1 ointment for 3 years. Each group was pasted once in the first day of the first, the middle and the last of the dog days of 2015, 2016 and 2017. Both groups were followed up once a year before the first day of the first of dog days of the next year after the end of treatment. The asthma control test (ACT) was used to evaluate the control of asthma for 3 years. The pulmonary function index [ the percentage of forced expiratory volume in predicted value (FEV 1%), the percentage of forced expiratory volume occupied by forced vital capacity (FEV 1/FVC) and peak expiratory flow (PEF)]and the number of acute attacks of asthma were compared between the two groups, and the skin reaction during acupoint application therapy was observed. Results The control rate of asthma increased year by year in the two groups. The control rate of the third follow-up in the experimental group was higher than that in the first follow-up ( P <0.05). The control rate of asthma in the experimental group was higher than that in the control group in the third follow-up ( P <0.05). The FEV 1%, FEV 1/FVC and PEF in the first, second and third follow-up of two groups were higher than those in the group before treatment ( P <0.05). The FEV 1%, FEV 1/FVC and PEF of two groups in the second and third follow-up were higher than those in the group in the first follow-up ( P <0.05). The FEV 1%, FEV 1/FVC and PEF in the experimental group in the third follow-up were higher than those in the second follow-up ( P <0.05). The FEV 1%, FEV 1/FVC and PEF in the experimental group were higher

关 键 词：哮喘 发作 穴位贴敷法 

分 类 号：R562.25[医药卫生—呼吸系统] R245.9[医药卫生—内科学]