经皮肾穿刺顺行球囊扩张术与开放手术治疗输尿管狭窄的meta分析  

Percutaneous ballon dilatation and traditional open surgery on benign ureteral stricture by meta analysis

作　　者：吴昊 刘川[1] 胡自力[1] 陈渝龙 张国彬 朱达伟 WU Hao;LIU Chuan;HU Zili;CHEN Yulong;ZHANG Guobin;ZHU Dawei(Department of Urinary Surgery,the Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第二医院泌尿外科,重庆400010

出　　处：《现代医药卫生》2019年第9期1331-1335,共5页Journal of Modern Medicine & Health

摘　　要：目的探讨经皮肾穿刺顺行法球囊扩张术与开放手术治疗良性输尿管狭窄的疗效及安全性。方法计算机检索PubMed、Cochrane Library、Eemase、CNKI、万方、维普及中国生物医学文献库,收集并筛选经皮肾穿刺顺行法球囊扩张术和传统开放手术治疗良性输尿管狭窄的随机对照试验(RCT),评估2种手术方案在手术时间、术中出血量、术后住院时间及总有效率等方面的差异。检索时间为建库至2018年5月28日。对文献进行筛选、资料提取和质量评价后,采用Revman 5.3软件进行meta分析。结果符合纳入标准的研究7篇,共427例患者,包括球囊扩张组207例,开放手术组220例。meta分析结果显示,2组术后治疗总有效率比较,差异无统计学意义(P>0.05);2组手术时间、术中出血量及术后住院时间比较,差异均有统计学意义(P<0.05)。结论经皮肾穿刺顺行法球囊扩张术与传统开放手术比较,可以在同等治疗效果下获得更高的手术的安全性。Objective To investigate the efficacy and safety of percutaneous nephrolithotomy with balloon dilatation and open surgery for benign ureteral stricture. Methods Computers were searched for PubMed,Cochrane Library,Embase,CNKI,Wanfang,and Wei to popularize the Chinese biomedical literature library.A randomized controlled trial (RCT) was performed to collect and screen percutaneous nephrolithotomy for balloon dilatation and conventional open surgery for benign ureteral stricture.The duration of surgery,intraoperative blood loss,postoperative hospital stay,and total were evaluated for the two surgical procedures.Differences in efficiency and other aspects.The search time is for the construction of the library until May 28,2018.Meta-analysis was performed using RevMan 5.3 software after screening,data extraction and quality evaluation of the literature. Results Seven studies were included in the inclusion criteria.A total of 427 patients,including 207 in the balloon-expanded group and 220 in the open surgery group.The meta-analysis showed that there was no significant difference in the total effective rate between the two groups ( P >0.05).There were significant differences in the operation time,intraoperative blood loss and postoperative hospital stay between the two groups ( P <0.05). Conclusion Compared with traditional open surgery,sacral percutaneous nephrolithotomy with balloon dilatation can achieve higher surgical safety under the same therapeutic effect.

关 键 词：经皮肾穿刺顺行法球囊扩张术 开放手术 输尿管狭窄 META分析 

分 类 号：R699.4[医药卫生—泌尿科学]