2型糖尿病患者空腹C肽水平与颈部血管病变的关系  

Correlation between fasting C-peptide level and cervical vasculopathy in patients with type 2 diabetes mellitus

作　　者：刘赵璧 张春容[2] LIU Zhao-bi;ZHANG Chun-rong(The Fifth Clinical College,Chongqing Medical University,Chongqing 402160,China;Department of Emergency Medicine,Yongchuan Hospital of Chongqing Medical University,Chongqing 402160,China)

机构地区：[1]重庆医科大学第五临床学院,重庆市402160 [2]重庆医科大学附属永川医院急诊医学科,重庆市402160

出　　处：《广西医学》2019年第8期948-950,共3页Guangxi Medical Journal

基　　金：重庆市卫生局医学科研计划(2011-2-286)

摘　　要：目的探讨2型糖尿病(T2DM)患者空腹C肽水平与颈部血管病变的关系。方法回顾性分析84例T2DM患者的临床资料,其中合并颈部血管病变的55例(观察组),未合并颈部血管病变29例(对照组)。比较两组患者的临床资料,采用Logistic回归模型分析空腹C肽水平与颈部血管病变的关系。结果观察组患者的年龄、病程、空腹C肽水平均高于对照组患者,而HDL-C水平低于对照组(均P <0. 05)。Logistic回归分析结果显示,年龄及空腹C肽水平是T2DM患者合并颈部血管病变的影响因素(均P <0. 05)。结论空腹C肽水平越高的T2DM患者合并颈部血管病变的风险越高。Objective To explore the correlation between fasting C-peptide level and cervical vasculopathy in patients with type 2 diabetes mellitus(T2DM). Methods The clinical data of 84 patients with T2DM were analyzed retrospectively,including 55(observation group) complicated with cervical vasculopathy and 29(control group) without cervical vasculopathy.Clinical data were compared between the two groups,and the correlation between fasting C-peptide level and cervical vasculopathy was analyzed by Logistic regression model. Results The observation group had higher age,course of disease,and fasting C-peptide level,as well as lower HDL-C level than the control group(all P <0.05).The results of Logistic regression analysis showed that age and fasting C-peptide level were influencing factors of T2DM patients complicated with cervical vasculopathy(all P <0.05). Conclusion T2DM patients with elevated level of fasting C-peptide face higher risk of complication of cervical vasculopathy.

关 键 词：2型糖尿病 颈部血管病变 空腹C肽 

分 类 号：R587.1[医药卫生—内分泌]