铁催化硼烷氢转移还原芳香硝基化合物  

Fe-Catalyzed Transfer Hydrogenation of Aromatic Nitro Compounds with Borane

作　　者：郭良程 周太刚 钟远海 宋浩 赵胜男 GUO Liang-cheng;ZHOU Tai-gang;ZHONG Yuan-hai;SONG Hao;ZHAO Sheng-nan(College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China;State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, China)

机构地区：[1]西南石油大学化学化工学院,四川成都610500 [2]西南石油大学油气藏地质及开发工程国家重点实验室,四川成都610500

出　　处：《合成化学》2019年第5期368-372,共5页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金青年基金资助项目(21602184);西南石油大学精细化学品青年科技创新团队(2017CXTD05)

摘　　要：发展了一种以硫酸铁为催化剂,硼烷四氢呋喃为氢源,在温和条件下实现了铁催化硼烷氢转移高效还原芳香硝基化合物的方法,合成了17个芳香胺衍生物,产率68%~90%,其结构经 1 H NMR和 13 C NMR确证。A general and efficient method for Fe-catalyzed transfer hydrogenation of aromatic nitro compounds with borane under mild reaction conditions was developed, using ferric sulfate as catalyst and borane tetrahydrofuran as hydrogen source. Seventeen aromatic amine derivatives were synthesized in 68%~90% yields. The structures were confirmed by 1 H NMR and 13 C NMR.

关 键 词：铁催化 硼烷四氢呋喃 芳香硝基化合物 芳香胺 氢转移 

分 类 号：TQ246.1[化学工程—有机化工] O62[理学—有机化学]