PET空间分辨率及其影响因素的研究进展  

Research progress on spatial resolution and influencing factors of PET

作　　者：王瑞 耿建华 WANG Rui;GENG Jian-hua(Department of Nuclear Medicine, PET/CT Center, National Cancer Center/National Clinical Research Center for Cancer/Chinese Academy of Medical Sciences and Peking Union Medical College/Cancer Hospital, Beijing 100021, China.)

机构地区：[1]国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院核医学科PET/CT中心,北京100021

出　　处：《中国医学装备》2019年第5期128-131,共4页China Medical Equipment

基　　金：国家自然科学基金(60572003)"PET图像中微小病灶的辩识与定量信息提取";科技部国际科技合作项目(2009DFA32960)"PET/CT脑分子影像研究与应用平台及针灸中枢机理探讨"

摘　　要：正电子发射计算机断层显像/CT(PET/CT)是现今肿瘤学不可或缺的成像技术,肿瘤的诊断、分期、分级、疗效评价以及预后均与正电子发射计算机断层显像(PET)图像的空间分辨率密不可分,是反映图像质量的重点指标。通过调研与综述PET空间分辨率及影响分辨率的主要因素正电子射程、探测器、飞行时间(TOF)、作用深度(DOI)和点扩散函数(PSF)新技术以及图像重建等因素对其影响的研究进展,为临床使用PET/CT提供借鉴。Positron emission tomography/CT(PET/CT) is an indispensable imaging technology in oncology of nowadays. The spatial resolution of PET image is interwovenness with the diagnosing, staging, grading, evaluation of curative effect as well as prognosis of tumors. And it is an key indicator that can reflect image quality. By investigating and reviewing the research progress on spatial resolution of PET and the main factors that affect the spatial resolution of PET included positron fire-range, detector, time of flight(TOF), depth of action(DOI), point spread function(PSF) and image reconstruction, this paper provides a reference for clinical use of PET/CT.

关 键 词：正电子发射断层术 空间分辨率 影响因素 

分 类 号：R197.3[医药卫生—卫生事业管理]