多核 ^(19)F磁共振成像研究进展  

Advances in Multi-core ^(19)F Magnetic Resonance Imaging

作　　者：王楚南 申宝忠[1] 吴丽娜[1] 孙夕林[1] 王凯[1] 王颖奕 WANG Chu-nan;SHEN Bao-zhong;WU Li-na;SUNXi-lin;WANG Kai;WANG Ying-yi(Medical Imaging Center,The Fourth AfSliated Hospital of Harbin Medical University & Molecular Imaging Research Center,Harbin Medical University,Harbin,Heilongjiang,150028,China)

机构地区：[1]哈尔滨医科大学附属第四医院医学影像中心&哈尔滨医科大学分子影像研究中心,黑龙江哈尔滨150028

出　　处：《现代生物医学进展》2019年第5期993-995,964,共4页Progress in Modern Biomedicine

基　　金：国家重点基础研究发展计划项目(2015CB931800);国家自然科学基金项目(81130028;31210103913);黑龙江省高校分子影像重点实验室基金资助

摘　　要：^(19)氟(^(19)F)的磁共振成像(MRI)研究可追溯到35年以上。在这段时间里,~1H磁共振成像的蓬勃发展使磁共振成为影像医学的支柱,但^(19)F磁共振成像研究的进展却较为缓慢。然而最近几年,^(19)F磁共振成像的研究受到了广泛的关注。在某种程度上,这是由于MR成像中软件与硬件的发展,更因为分子影像学的概念的提出与发展。本文将对^(19)F多核磁共振成像的应用,特别是使用全氟化碳纳米成像探针的19F多核磁共振成像进行综述。The research roots of 19 fluorine(19F)magnetic resonance imaging(MRI)date back over 35 years.Over that time span,1H imaging flourished and become the pillars of imaging medicine,but 19F magnetic resonance imaging research progress is relatively slow.Recent years,19F Magnetic resonance imaging research has received extensive attention.This is due to MR imaging software and hardware development,but also because the concept of molecular imaging proposed and development.This paper reviewed applications of 19F multi-nuclear magnetic resonance imaging,particularly focused on perfluorocarbon nanoparticles of 19F multinuclear magnetic resonance imaging.

关 键 词：氟 磁共振 全氟化碳 

分 类 号：R445.2[医药卫生—影像医学与核医学]