抗核抗体与椎-基底动脉供血不足患者中医证型的关系  

Relationship between Antinuclear Antibodies and TCM Patterns of Vertebrobasilar Insufficiency

作　　者：王娜莎 韩波[1] WANG Nasha;HAN Bo(The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China)

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《西部中医药》2019年第3期90-92,共3页Western Journal of Traditional Chinese Medicine

基　　金：辽宁省科学技术计划项目(编号2017010186-301)

摘　　要：目的:探讨抗核抗体(ANA)与椎-基底动脉供血不足(VBI)患者中医证型的关系。方法:采用间接免疫荧光法检测VBI组(106例)和健康对照组(30例)的血清ANA。结果:1)VBI组ANA阳性比例高于健康对照组,差异有统计学意义(P<0.05);2)VBI组患者各证型除痰湿中阻证组外,其余各证型组ANA阳性率均高于健康对照组,各证型ANA阳性比例高低依次为:气血亏虚证>肾精不足证>肝阳上亢证>痰湿中阻证>健康对照组;气血亏虚证、肾精不足证与健康对照组ANA阳性比例分布比较差异具有统计学意义(P<0.05)。结论:VBI患者各证型与ANA阳性比例高低有一定联系,早期ANA检测可评估VBI患者是否存在免疫系统紊乱情况。Objective: To discuss the relationship between antinuclear antibodies (ANA) and TCMpatterns of vertebrobasilar insufficiency (VBI). Methods: ANA in the serum of VBI group (106 cases) and healthy control group (30 cases) was detected using indirect immunofluorescence (IFL). Results: 1) VBI group was higher than healthy control group in ANA positive rate, and the difference had statistical meaning (P<0.05);2) VBI group was higher than healthy control group in ANA positive rates of different patterns except phlegm-damp obstruction pattern, the positive rates of ANA of different patterns ranked fromhigh to low:Qi and blood deficiency pattern>kidney-essence insufficiency pattern>liver-Yang hyperactivity pattern>phlegm-damp obstruction pattern>healthy control group;the difference has been found when Qi and blood insufficiency pattern and kidney-essence insufficiency pattern were compared with healthy control group in ANA positive rate (P<0.05). Conclusion: Different patterns of VBI patients show certain connections to ANA positive rates, early determination of ANA could be used to assess whether the disorders existed in immune systemof VBI patients.

关 键 词：椎-基底动脉供血不足 中医证型 抗核抗体 

分 类 号：R255.3[医药卫生—中医内科学]