同型半胱氨酸异常是男性高尿酸血症的促进因素  

Homocysteine abnormality,a contributing factor to male hyperuricemia

作　　者：黄英[1,2] 王一珏 欧良英 庹有烈 郎桂荣 张建新 HUANG Ying;WANG Yi-jue;OU Liang-ying;TUO You-lie;LANG Gui-rong;ZHANG Jian-xin(West China School of Public Health and West China Fourth Hospital,Sichuan University /Sichuan Reproductive Health Research Center Affiliated Reproductive Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]四川大学华西公共卫生学院/四川大学华西第四医院,四川成都610041 [2]四川省生殖健康研究中心附属生殖专科医院,四川成都610000 [3]成都中医大体检医院,四川成都610000

出　　处：《现代预防医学》2019年第9期1644-1649,共6页Modern Preventive Medicine

摘　　要：目的探讨人群高尿酸血症的现状及影响因素。方法对2017年在成都中医大体检医院接受健康体检、并且收集到11项健康检测指标的1 487例对象进行分析,采用卡方检验和logistic回归分析高尿酸血症的影响因素。结果高尿酸血症检出率达27.1%,男性高尿酸检出率是女性的2.7倍。饮酒是男性高尿酸血症的保护因素;吸烟、同型半胱氨酸是其促进因素。甘油三酯、脂肪肝是女性高尿酸血症的危险因素;高密度脂蛋白是其保护因素。结论吸烟、同型半胱氨酸异常是男性高尿酸血症的危险因素;甘油三脂异常、脂肪肝是女性高尿酸血症的危险因素。Objective To investigate the current status and influencing factors of hyperuricemia in the population. Methods 11 health tests of 1 487 subjects who received the physical examination at the Chengdu Traditional Chinese Medicine Hospital in 2017 were collected and analyzed. Chi - square test and logistic regression were used to analyze the influencing factors to hyperuricemia. Results The detection rate of hyperuricemia was 27. 1%,and the detection rate of male high uric acid was 2. 7 times that of female. Alcohol consumption was a protective factor for male hyperuricemia, while smoking and homocysteine abnormalities were contributing factors. Abnormal triglycerides and fatty liver were risk factors for hyperuricemia in women,while high - density lipoprotein was a protective factor. Conclusion Smoking and homocysteine abnormalities are risk factors for hyperuricemia in men,while abnormal triglyceride and fatty liver are risk factors for hyperuricemia in women.

关 键 词：同型半胱氨酸 高尿酸血症 影响因素 

分 类 号：R181.23[医药卫生—流行病学]