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作 者:陈惠南[1] 梁见弟[1] 王彬[1] CHEN Hui-nan;LIANG Jian-di;WANG-Bin(Department of Reproductive Medicine, Dongguan People′s Hospital, Guangdong Province, Dongguan 523018, China)
机构地区:[1]广东省东莞市人民医院生殖医学科,广东东莞523018
出 处:《中国当代医药》2019年第12期209-211,共3页China Modern Medicine
基 金:广东省东莞市医疗卫生科技计划一般项目(2016105101019)
摘 要:目的探讨综合护理干预对实施黄体期卵巢刺激方案患者卵巢功能下降的应用效果。方法选择2016年2月~2018年2月在我院接受黄体期卵巢刺激方案的120例卵巢功能下降患者作为研究对象,按照随机数字表法分为观察组和对照组,每组各60例。对照组给予一般护理干预,观察组给综合护理干预。比较两组促性腺激素(Gn)使用时间、使用量及绒毛膜促性腺激素(HCG)注射日雌二醇(E_2)水平、获卵数、可利用胚胎数情况,临床妊娠率、早期流产率、周期取消率。结果观察组Gn使用时间长于对照组,Gn使用量和HCG注射日E_2水平高于对照组,获卵个数和可利用胚胎数多于对照组,临床妊娠率高于对照组,差异均有统计学意义(P<0.05)。结论综合护理干预可显著提高接受黄体期卵巢刺激方案治疗的卵巢功能下降患者HCG注射日E_2水平、获卵数、可利用胚胎数,改善临床妊娠率。Objective To explore the effect of comprehensive nursing intervention on ovarian dysfunction in patients undergoing luteal phase ovarian stimulation program. Methods From February 2016 to February 2018, 120 patients with ovarian dysfunction who received luteal phase ovarian stimulation program in our hospital were selected as subjects for observation. According to the random number table method, they were divided into observation group and control group, 60 cases in each group. The control group was given general nursing intervention, while the observation group was given comprehensive nursing intervention on the basis of general nursing. The time and amount of gonadotrophic hormone (Gn) use, the estradiol level on the day of (HCG) injection, the number of eggs harvested, the number of embryos available, the clinical pregnancy rate, the early abortion rate and the cancellation rate of cycles were compared between the two groups. Results The Gn use time of the observation group was longer than that of the control group, Gn use and estradiol level on the day of HCG injection were higher than those in the control group, the number of eggs and available embryos was more than that of the control group, the clinical pregnancy rate was higher than that of the control group, the differences were statistically significant (P<0.05). Conclusion Comprehensive nursing intervention can significantly improve the level of estradiol injection daily, the number of eggs obtained, the number of embryos available, and the clinical pregnancy rate in patients with decreased ovarian function treated with luteal stage ovarian stimulation.
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