大剂量地塞米松治疗成人原发性免疫性血小板减少症合并糖尿病的效果  

Effect of High-dose Dexamethasone in the Treatment of Adult Primary Immune Thrombocytopenia Complicated with Diabetes

作　　者：崔璐[1] CUI Lu(Department of Hematology,Changchun Central Hospital,Changchun,Jilin Province,130000 China)

机构地区：[1]长春市中心医院血液内科,吉林长春130000

出　　处：《糖尿病新世界》2019年第6期89-90,共2页Diabetes New World Magazine

摘　　要：目的探讨大剂量地塞米松治疗成人原发性免疫性血小板减少症合并糖尿病的效果。方法选取2016年5月—2018年5月该科收治的ITP合并糖尿病患者22例,随机分为两组各11例,观察组采用大剂量地塞米松,对照组采用泼尼松。结果观察组总有效率为81.8%,显著优于对照组63.6%(P<0.05);观察组FPG显著低于对照组,PLT明显高于对照组(P<0.05)。结论 ITP合并糖尿病患者采用大剂量地塞米松治疗效果显著,对血糖无明显影响,安全性高,值得应用。Objective To investigate the effect of high-dose dexamethasone in the treatment of adult primary immune thrombocytopenia with diabetes.Methods Twenty-two patients with ITP and diabetes mellitus admitted to our department from May 2016 to May 2018 were randomly divided into two groups:11 patients each.The observation group received high-dose dexamethasone and the control group received prednisone.Results The total effective rate of the observation group was 81.8%,which was significantly better than that of the control group(63.6%)(P<0.05).The FPG of the observation group was significantly lower than that of the control group,and the PLT was significantly higher than the control group(P<0.05).Conclusion ITP patients with diabetes mellitus have a significant effect on high-dose dexamethasone,no significant effect on blood glucose,high safety and worthy of application.

关 键 词：地塞米松 原发性免疫性血小板减少症 糖尿病 

分 类 号：R587.1[医药卫生—内分泌]