葡萄球菌性烫伤样皮肤综合征30例临床分析  

Clinical analysis of 30 cases of staphylococcal scalded skin syndrome

作　　者：常瑞雪 张思平 王玲[1] 陆闻生 CHANG Ruixue;ZHANG Siping;WANG Ling;LU Wensheng(Department of Dermatology,The First Affiliated Hospital of USTC,Anhui Provincial Hospital,Hefei,Anhui 230001,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)皮肤科,安徽合肥230001

出　　处：《安徽医药》2019年第6期1121-1123,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨匍萄球菌性烫伤样皮肤综合征发病的诱发因素、临床特点及治疗方法。方法回顾性分析中国科学技术大学附属第一医院皮肤科2010年5月至2016年12月收住的30例葡萄球菌烫伤样皮肤综合征病儿的临床特点。结果 30例葡萄球菌性烫伤样皮肤综合征病儿≤3岁的占总病例的73.3%;病儿多有弥漫性潮红斑、松弛性大疱或大片表皮剥脱,口周有放射状皲裂,触痛明显。16例病儿发病前有明确诱因;30例均应用抗生素治疗,19例联合应用糖皮质激素治疗,6例联合应用人免疫球蛋白,所有病儿均在11 d内治愈出院,住院时间(6.4±2.1) d。结论匍萄球菌烫伤样皮肤综合征是一种重症感染性疾病,在正确选用抗生素的基础上,应用糖皮质激素及丙种球蛋白,并加强护理,可获得满意疗效。Objective To investigate the factors,clinical features and treatments of staphylococcal scalded skin syndrome(SSSS).Methods Data of 30 hospitalized cases with SSSS treated in Department of Dermatology of The First Affiliated Hospital of USTC from May 2010 to December 2016 were retrospectively reviewed.Results Of the 30 patients,children less than 3 years old accounted for 73.3%.The infants mostly presented with diffused flushing erythema,lusitropic bulla or a sheet of superficial exfoliation and specific perioral radiated rhagades,which made the infants painful.There was clear inducement for 16 infants before the onset of the disease.All the cases were given antibiotics,19 of which were also treated with corticosteroids and 6 with intravenous immunoglobulin(IVIG).All the patients were cured and discharged within 11 days,with a hospital stay of(6.4±2.1)days.Conclusion SSSS is a severe inflammatory disease which could be cured with corticosteroid,IVIG as well as intensive care on the basis of appropriate antibiotics.

关 键 词：葡萄球菌性烫伤样皮肤综合征 临床特点 治疗 

分 类 号：R753[医药卫生—皮肤病学与性病学]