复方利多卡因乳膏与右美托咪定抑制全身麻醉拔管期呛咳反应效果比较  

Comparison of the effect of compound lidocaine cream and dexmedetomidine in inhibiting cough reaction during extubation of general anesthesia

作　　者：王婷[1] 郑诗 刘燕君[1] 黄琳[1] 刘美丽[1] 胡琳[1] Wang Ting;Zheng Shi;Liu Yanjun;Huang Lin;Liu Meilin;Hu Lin(Department of Anesthesiology,the Second People's Hospital of Guangdong Province 510310)

机构地区：[1]广东省第二人民医院麻醉科,510310

出　　处：《中国社区医师》2019年第13期80-80,83,共2页Chinese Community Doctors

摘　　要：目的:探讨复方利多卡因乳膏与右美托咪定抑制全身麻醉拔管期呛咳反应差异,指导临床选择合适的麻醉药物。方法:收治甲状腺手术患者120例,随机分为L组、D组和对照组(C组)各40例。L组气管导管前1/2和套囊表面均匀涂抹复方利多卡因乳膏,D组气管导管表面涂抹液状石蜡并从气管插管后至手术结束前30 min持续静脉滴注右美托咪定,C组气管导管表面涂抹液状石蜡。比较相关指标。结果:L组和D组拔管期间呛咳反应发生率和血液动力学指标明显低于C组,且呛咳反应程度也明显低于C组,差异有统计学意义(P<0.05)。结论:复方利多卡因乳膏较右美托咪定更能明显降低术后不良反应发生率。Objective:To investigate the difference between compound lidocaine cream and dexmedetomidine in inhibiting cough response during extubation of general anesthesia,and to guide clinical selection of appropriate anesthesia drugs.Methods:120 cases of thyroid surgery patients were selected,they were randomly divided into the L group,the D group and the control group(the group C)with 40 cases in each group.In the group L,compound lidocaine cream was uniformly applied on the surface of the endotracheal tube 1/2 and the thimble.In the group D,liquid paraffin was applied on the surface of tracheal catheter and dexmedetomidine was continuously intravenously drip from the tracheal intubation to 30 min before the end of surgery.The group C tracheal catheters were coated with liquid paraffin,we compared the relevant indicators.Results:The incidence and hemodynamic indexes of chokehold reaction in extubation period in the group L and the group D were significantly lower than those in the group C,and the degree of chokehold reaction was significantly lower than that in the group C,the difference was statistically significant.Conclusion:Compound lidocaine cream can significantly reduce the incidence of postoperative adverse reactions compared with dexmedetomidine.

关 键 词：利多卡因 软膏 右美托咪定 麻醉 

分 类 号：R614[医药卫生—麻醉学]