创伤性脑梗死相关危险因素分析  

Analysis of Risk Factors Related to Traumatic Cerebral Infarction

作　　者：赵文秀 刘小军[1] 王文涛[1] 郭燕[1] 祁景[1] ZHAO Wen-xiu;LIU Xiao-jun;WANG Wen-tao;GUO Yan;QI Jing(Department of Critical Care Medicine,Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan Province,450014 China)

机构地区：[1]郑州大学第二附属医院重症医学科,河南郑州450014

出　　处：《系统医学》2019年第6期1-3,共3页Systems Medicine

摘　　要：目的探究创伤性脑梗死(PTCI)的相关危险因素,并总结相应防治对策。方法回顾性分析该院2015年6月—2018年6月收治的符合条件的432例颅脑外伤患者,其中发生PTCI患者31例,对所有患者的年龄、性别、脑疝形成、蛛网膜下腔出血、去骨瓣减压术、应用止血药物时间、休克、糖尿病、D-二聚体、血沉、血小板水平及功能等发生PTCI的相关因素进行单因素分析,对危险因素进行多因素回归分析。结果 432例患者中,31例发生PTCI,发病率为7.18%;患者高龄、脑疝形成、蛛网膜下腔出血、低血压休克、应用止血药物(>3 d)、糖尿病、高D-二聚体、高血沉、血小板功能亢进是发生PTCI可能的危险因素,差异有统计学意义(P<0.05);其中高龄(OR=4.074,P<0.05,95%CI2.366～9.741)、脑疝形成(OR=3.561,P<0.05,95%CI1.962～8.054)、蛛网膜下腔出血(OR=2.478,P<0.05,95%CI1.269～4.548)、低血压休克(OR=5.317,P<0.05,95%CI3.821-10.649)、糖尿病(OR=2.355,P<0.05,95%CI1.293～5.421)、高D-二聚体(OR=3.804,P<0.05,95%CI3.174-8.623)、血小板功能亢进(OR=7.324,P<0.05,95%CI4.861～11.846)与PTCI的发生密切相关。结论颅脑外伤患者存在高龄、脑疝形成、蛛网膜下腔出血、低血压休克、糖尿病、高D-二聚体、血小板功能亢进均是PTCI的危险因素,应及早重视并预防。Objective To explore the related risk factors of traumatic cerebral infarction(PTCI)and summarize the corresponding prevention and treatment strategies.Methods A retrospective analysis of 432 patients with craniocerebral trauma admitted to our hospital from June 2015 to June 2018,including 31 patients with PTCI,age,gender,cerebral palsy,subarachnoid univariate analysis of PTCI related factors,such as luminal hemorrhage,decompressive craniectomy,application of hemostatic drug time,shock,diabetes,D-dimer,erythrocyte sedimentation rate,platelet level and function,and multivariate regression analysis of risk factors were performed.Results Of the 432 patients,31 had PTCI,the incidence rate was 7.18%.The patient with elder age,cerebral palsy,subarachnoid hemorrhage,hypotension shock,application of hemostatic drugs(>3 days),diabetes,high D-dipolymer,hyperspore,and platelet hyperfunction were risk factors for PTCI,and the difference was statistically significant(P<0.05).Among them,advanced age(OR=4.074,P<0.05,95%CI2.366-9.741),cerebral palsy formation(OR=3.561,P<0.05,95%CI1.962-8.054),subarachnoid hemorrhage(OR=2.478,P<0.05,95%CI 1.269-4.548),hypotensive shock(OR=5.317,P<0.05,95%CI3.821-10.649),diabetes(OR=2.355,P<0.05,95%CI1.293-5.421),high D-dimer(OR=3.804,P<0.05,95%CI3.174-8.623),platelet hyperfunction(OR=7.324,P<0.05,95%CI4.861-11.846)was closely related to the occurrence of PTCI.Conclusion The age of cerebral trauma patients,cerebral palsy,subarachnoid hemorrhage,hypotension shock,diabetes,high D-dipolymer,and platelet hyperfunction are all risk factors for PTCI,which should be paid attention to and prevented early.

关 键 词：创伤 脑损伤 脑梗死 

分 类 号：R651[医药卫生—外科学]