产妇先兆性流产的发生与妊娠生殖道感染的相关性  

Analysis on the correlation between the occurrence of maternal threatened abortion and gestational reproductive tract infections

作　　者：李玲[1] 刘兰涛 LI Ling;LIU Lantao(Department of Obstetrics and Gynecology,Deyang People's Hospital,Deyang 618000,Sichuan,China)

机构地区：[1]德阳市人民医院妇产科,四川德阳618000

出　　处：《西部医学》2019年第5期737-740,745,共5页Medical Journal of West China

摘　　要：目的探讨产妇在妊娠期出现生殖道感染与发生先兆性流产之间的关系。方法选取2015年7月～2016年7月我院收治的62例早期先兆流产产妇设为观察组,选取同期在我院接受分娩的正常孕妇60例为对照组,行回顾性分析。对两组产妇进行白带常规镜检、解脲支原体(UU)以及沙眼衣原体(CT)阳性率检测。结果观察组白带常规白细胞百分率、清洁度百分率、念珠菌阳性率与对照组比较差异均有统计学意义(P<0.05),两组乳酸杆菌阳性率之间的差异无统计学意义(P>0.05);观察组患者感染UU、CT总百分比与对照组比较明显较高,差异有统计学意义(P<0.05);观察组患者炎症因子水平IL-1、TNF-α和IL-8明显高于对照组(P<0.05)。结论先兆性流产产妇的白带异常率、解脲支原体阳性率、沙眼衣原体阳性率和炎症因子水平均明显高于正常产妇,可能是先兆性流产发生的重要原因之一。因此应注意加强产前检查,控制产妇孕激素水平,采取积极有效的方法治疗生殖道感染,改善不良妊娠结局。Objective To explore the correlation between gestational reproductive tract infections and the occurrence of maternal threatened abortion.Methods A retrospective analysis was conducted.62 pregnant women with threatened abortion treated in our hospital from July 2015 to July 2016 were selected as the observation group.Another 60 normal pregnant women who received delivery in our hospital during the same period were selected as the control group.The pregnant women in both two groups received the detection of the positive rate of leucorrhea routine microscopy,ureaplasma urealyticum (UU) and chlamydia trachomatis (CT).Results For leucorrhea routine examination items,the percentage of white blood cells,the percentage of cleanliness Ⅲ-Ⅳ and candida positive rate in the observation group were significantly higher than those in the control group,and the differences were statistically significant ( P <0.05).There was no significant difference in the positive rate of lactobacillus between two groups ( P >0.05).The total percentage of UU and CT infection in the observation group was significantly higher than the control group,and the difference was statistically significant ( P <0.05).The levels of IL-1,TNF-alpha and IL-8 in the observation group were significantly higher than those in the control group ( P <0.05).Conclusion The abnormal vaginal discharge rate,UU positive rate and CT positive rate and inflammatory factor levels in pregnant women with threatened abortion were significantly higher than those in normal pregnant women,which may be the important causes of threatened abortion.Therefore,the pregnant women should pay attention to strengthening the prenatal examination,and take active and effective treatment to improve the adverse pregnancy outcomes.

关 键 词：先兆性流产 妊娠 生殖道感染 相关性 

分 类 号：R714.21[医药卫生—妇产科学]