短暂性与持续性急性肾损伤诊断及预后  

Diagnosis and prognosis of transient and persistent acute kidney injury

作　　者：李青霖[1] 周飞虎[1] LI Qing-Lin;ZHOU Fei-Hu(Department of Critical Care Medicine, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China)

机构地区：[1]解放军总医院第一医学中心重症医学科,北京100853

出　　处：《中华老年多器官疾病杂志》2019年第5期385-389,共5页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：国家老年疾病临床医学研究中心课题(NCRCG-PLAGH-2017008);吴阶平医学基金会恒睿基金重点课题(320675018383)~~

摘　　要：急性肾损伤(AKI)是临床常见的危急重症,死亡率高,预后差,其诊断有赖于血肌酐的升高和尿量的减少。AKI目前尚无有效的治疗方法,严重时需进行肾脏替代治疗。2002年至2017年期间先后4次更新了AKI指南与共识,这对于早期识别AKI患者起到积极作用。但现有的AKI定义中,并未区分短暂性AKI和持续性AKI,现就目前短暂性与持续性AKI病理学、诊断治疗及远期预后的研究进展进行综述。Acute kidney injury(AKI) is a common critical condition with high mortality and poor prognosis. Currently, its diag-nosis relies on the increase in serum creatinine and the decrease in urine output. No specific therapy is available for it and renal replacement therapy is needed for severe patients. The AKI Guidelines and Consensus, updated four times from 2002 to 2017, exerted positive effect on early identification of AKI patients. However, the present definition of AKI does not make a distinction between transient and persistent AKI. This paper reviewed the progress in their pathology, clinical manifestations, diagnosis and treatment.

关 键 词：急性肾损伤 短暂性 持续性 诊断 治疗 预后 

分 类 号：R692[医药卫生—泌尿科学] R592[医药卫生—外科学]