临床治疗性试验研究的评价原则  

Points on evaluation of medical papers about clinical trials

作　　者：王雪萍[1] 吕青远 王彩霞[1] 张美 和雨璇 陈巧云 叶大训 WANG Xue-Ping;LYU Qing-Yuan;WANG Cai-Xia;ZHANG Mei;HE Yu-Xuan;CHEN Qiao-Yun;YE Da-Xun(Editorial Office of Chinese Journal of Multiple Organ Diseases in the Elderly, Department of Cardiology, First Medical Center,Chinese PLA General Hospital, Beijing 100853, China)

机构地区：[1]解放军总医院第一医学中心心血管内科<中华老年多器官疾病杂志>编辑部,北京100853

出　　处：《中华老年多器官疾病杂志》2019年第5期398-400,共3页Chinese Journal of Multiple Organ Diseases in the Elderly

摘　　要：临床科研质量与科研设计水平密切相关。医学期刊审稿专家与编辑作为医学研究共同体不可或缺的部分,一定要担负起为医学提供最可靠临床研究证据的重任;而不能允许发表那些研究方法错误、结论不可靠、不能提供最佳证据的研究方法和科研成果。临床科研设计类型繁多,到底选用哪种研究设计,主要取决于要解决问题的性质。不同的研究各具特色,各有侧重,进行评价时应有所区分。本文主要从研究对象、处理因素、观察指标、样本大小、统计学及临床意义兼顾等方面介绍了临床治疗性试验研究的评价原则,以期引起医学期刊审稿专家、编辑和广大从事临床科研医务工作者的重视。Quality of clinical research is related closely to the study design. Referees and editors from medical journals, as an essential part of medical research community, must shoulder the responsibility to have the most reliable and scientific evidence for medical sciences published, rather than the inferior studies with incorrect study design and unreliable results. The studies should be evaluated based on its nature. In this paper, we introduced the points on evaluating the medical papers about clinical trials from several aspects, like subjects enrollment, treatment measures, observed parameters, sample size, balance between statistical and clinical significance etc. We aimed to call attention from medical paper referees, editors, as well as researchers themselves.

关 键 词：临床科研设计 评价 医学文献 临床治疗性试验 

分 类 号：R195.1[医药卫生—卫生统计学] R237.5[医药卫生—卫生事业管理]