艾灸对类风湿关节炎患者的抗炎镇痛作用观察  

Observation of Anti-Inflammatory and Analgesic Effects of Moxibustion on RA Patients

作　　者：周旻庆 武平[1] 李媛[2] 谭会 廖晨希 陈白露 代静杨 白玉[1] 熊燕[1] HOU Minqing;WU Ping;LI Yuan;TAN Hui;LIAO Chenxi;CHEN Bailu;DAI Jingyang;BAI Yu;XIONG Yan(Chengdu University of TCM, Chengdu 610075, Sichuan, China;The Affiliated Hospital of ChengduUniversity of TCM,Chengdu 610075,Sichuan,China;The People's Hospital of Baoan,Shenzhen 518102,Guangdong, China;TCM Affiliated Hospital of Southwest Medical University,Luzhou 646000, Sichuan, China)

机构地区：[1]成都中医药大学针灸推拿学院,四川成都610075 [2]成都中医药大学附属医院,四川成都610075 [3]深圳市宝安区中心医院,广东深圳518102 [4]西南医科大学附属中医医院,四川泸州646000

出　　处：《辽宁中医杂志》2019年第4期832-835,I0003,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81373738);四川省科技计划项目(重大前沿项目)(2017JY0016)

摘　　要：目的:观察艾灸对类风湿关节炎(RA)患者滑膜病变的影响,探讨艾灸对RA的抗炎镇痛作用。方法:将40例RA患者,随机分为治疗组和对照组各20例。对照组口服常规西药甲氨蝶呤或来氟米特,治疗组在此基础上,配合艾灸"足三里""肾俞"及阿是穴,每周2次,4周为1疗程,共治疗3个疗程。应用高频超声技术检测治疗前后RA患者双手关节滑膜病变情况,分别记录滑膜厚度、关节积液、血流信号及骨质破坏的关节数和评分。并对RA患者治疗前后的临床症状、实验室指标进行评价。结果:治疗后治疗组对RA患者滑膜厚度、关节积液及血流信号的改善优于对照组(P <0. 05)。治疗后治疗组对RA患者VAS评分、DAS28评分、压痛指数、肿胀指数、证候积分和实验室指标的改善优于对照组(P <0. 05)。结论:艾灸能够增强常规西药改善RA患者的滑膜病变,对RA具有抗炎增效作用。Objective: To observe the effect of moxibustion on synovial lesions in patients with rheumatoid arthritis( RA) and explore the anti-inflammatory and analgesic effects of moxibustion on RA. Methods: Forty patients with RA were randomly divided into treatment group and control group,20 patients in each one. The patients in the control group were treated with methotrexate or leflunomide while for the control group,besides the above therapeutic measures,patients were treated with moxibustion at Zusanli( ST36),Shenshu( BL23) and Ashi acupoint. The treatment was given twice a week,four weeks for a period,and totally 3 periods treatment was performed. Synovial thickness,joint effusion,blood flow signals and bone erosion of the RA patients’ double hand joints were tested by high frequency ultrasonography before and after treatment,and clinical symptoms and laboratory indexes were evaluated at the same time. Results: After treatment,the improvement of synovial thickness,joint effusion and blood flow in the treatment group were significantly better than those in the control group( all P < 0. 05). VAS score,DAS28 score,tenderness index,swelling index,symptom integral and laboratory indexes in the treatment group were improved more obviously compared with those in the control group( all P < 0. 05). Conclusion: Moxibustion can enhance the routine western medicine to improve the synovial lesions of RA patients and has anti-inflammatory and synergistic effect on RA.

关 键 词：艾灸 类风湿关节炎 滑膜病变 高频超声技术 

分 类 号：R593.22[医药卫生—内科学]