颈动脉超声检查对糖尿病合并冠心病患者的应用价值研究  

Value of Carotid Ultrasonography in Application of Patients with Diabetes Mellitus Complicated by Coronary Heart Disease

作　　者：刘超[1] 魏志强 何翔[1] 张磊[1] 王艳平 王燕[1] 王佳[1] LIU Chao;WEI Zhi-qiang;HE Xiang;ZHANG Lei;WANG Yan-ping;WANG Yan;WANG Jia(CT Scan Room, Central Hospital of Cangzhou City, Cangzhou, Hebei 061000, China;Department of MRI Examination, People's Hospital of Hejian County, Hejian, Hebei 062450, China)

机构地区：[1]沧州市中心医院CT诊断科,河北沧州061001 [2]河间市人民医院核磁共振科,河北沧州062450

出　　处：《解放军医药杂志》2019年第5期75-77,共3页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：河北省卫生厅科研基金项目(20191270)

摘　　要：目的探讨颈动脉超声检查对糖尿病合并冠心病患者的应用价值。方法选择2016年10月—2017年10月我院收治的初诊冠心病患者181例,根据是否合并2型糖尿病分为观察组79例,对照组102例。对2组的血压、血脂、糖化血红蛋白、冠脉造影结果及颈动脉超声结果进行分析,观察Gensini积分与Crouse、CA积分和斑块个数的相关性。结果 2组血压、胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇比较差异无统计学意义(P>0.05),观察组甘油三酯、糖化血红蛋白水平高于对照组(P<0.05)。观察组Gensini积分、3支病变、弥漫性病变发生率均高于对照组(P<0.05)。观察组CA积分、Crouse积分、斑块个数均高于对照组,(P<0.05)。Gensini积分与Crouse、CA积分和斑块个数呈正相关(r=0.25、0.36、0.27,P<0.01)。结论对于冠心病的高危人群,尤其是2型糖尿病患者,可通过颈动脉超声进行筛查,以达到早期诊断,早期控制疾病进展及提高治疗效率的目的。Objective To investigate value of carotid ultrasonography in application of patients with diabetes mellitus complicated by coronary heart disease. Methods A total of 181 patients with coronary heart disease by preliminary diagnosis admitted during October 2016 and October 2017 were divided into observation group ( n =79) and control group ( n =102) according to whether or not combination of type 2 diabetes mellitus. In two groups, levels of blood pressure, blood lipid, glycosylated hemoglobin, coronary angiography and carotid artery ultrasound results were analyzed, and correlations among Gensini score with Rouse and CA scores and plaque number were observed. Results There were no significant differences in blood pressure, cholesterol, high density lipoprotein cholesterol or low density lipoprotein cholesterol between two groups ( P >0.05). In observation group, levels of triglyceride and glycosylated hemoglobin were significantly higher ( P <0.05);Gensini score, incidence rates of three vessel lesions and diffuse lesions were significantly higher ( P <0.05);CA score, Crouse score and plaques number were significantly higher than those in control group ( P <0.05). Gensini score was positively correlated with Crouse score, CA score and plaques number ( r =0.25, 0.36, 0.27, P <0.01). Conclusion Screening by carotid ultrasound can be used for high-risk patients with coronary heart disease, especially for patients with type 2 diabetes mellitus in order to early diagnosis, early control of disease progress and improve treatment efficiency.

关 键 词：糖尿病  2型 冠心病 颈动脉超声 冠状血管造影术 

分 类 号：R587.1[医药卫生—内分泌]