MR灌注加权成像在急性脑梗死患者临床诊治中的应用研究  

Application of MR perfusion weighted imaging in clinical diagnosis and treatment of acute cerebral infarction

作　　者：王盛磊 朱幼玲 唐敏 Wang Shenglei;Zhu Youling;Tang Min(Department of Neurology,the Third Affiliated Hospital of Anhui Medical University (First People′s Hospital of Hefei),Hefei 230000,China)

机构地区：[1]安徽医科大学第三附属医院(合肥市第一人民医院)神经内科,合肥230000

出　　处：《中国脑血管病杂志》2019年第5期274-277,共4页Chinese Journal of Cerebrovascular Diseases

基　　金：合肥市卫生和计划生育委员会第五周期医学重点学科建设项目[合卫科教(2016)256号];合肥市科学技术局"借转补"科研项目[合科(2017)112号]

摘　　要：MR灌注加权成像是一种反映组织微血管分布和血流灌注情况的MR功能成像技术。随着MR技术的发展,灌注加权成像广泛应用于脑梗死的临床诊治中。动态磁敏感对比技术能够判断缺血半暗带,评估急性脑梗死侧支循环的程度;动态对比增强技术能够反映血-脑屏障的完整性,评价脑梗死患者的出血转化以及侧支循环的建立;动脉自旋标记技术也可用于判断缺血半暗带、发现梗死灶周围的灌注情况和评估侧支循环。作者对MR灌注加权成像在急性脑梗死患者临床诊治中的研究进展进行综述。Magnetic resonance (MR) perfusion weighted imaging (PWI) is a functional MR imaging technique that reflects the distribution of tissue microvessels and blood perfusion.In recent years,with the development of MR technology,PWI has been widely used in the clinical diagnosis and treatment of cerebral infarction.Dynamic susceptibility contrast-enhanced imaging can delineate the ischemic penumbra and evaluate the compensation of collateral circulation.Dynamic contrast-enhanced imaging can reflect the integrity of blood-brain barrier,evaluate risk of the hemorrhagic transformation and the compensation of collateral circulation.The technique of arterial spin labeling can also be used to delineate ischemic penumbra,confirm the perfusion around the infarct core,and to evaluate the collateral circulation.The relevant studise on MR PWI in acute cerebral infarction will be reviewed.

关 键 词：磁共振成像 动态磁敏感对比 动态对比增强 动脉自旋标记 脑梗死 综述 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]