联二萘甲酰胺催化合成吡唑啉酮衍生物  

Synthesis of Pyrazolone Derivative Catalyzed by Binaphtyl Carboxamides

作　　者：王文琛[1] 王金娟[1] 杨志翔[1] 裴学海 陈治明[1] Wang Wenchen;Wang Jinjuan;Yang Zhixiang;Pei Xuehai;Cheng Zhiming(Key Laboratory of Functional Materials Chemistry of Guizhou Province,School of Chemistry and Materials Science,Guizhou Normal University,Guiyang,Guizhou 550001,China)

机构地区：[1]贵州师范大学化学与材料科学学院贵州省功能材料重点实验室,贵州贵阳550001

出　　处：《化学世界》2019年第4期236-242,共7页Chemical World

基　　金：国家自然科学基金(No.21362006)资助项目

摘　　要：合成具有"多氢键、多功能"电子效应可调的联二萘甲酰胺类催化剂,并用于催化合成吡唑啉酮衍生物。研究表明,在室温下3,3′-二[(R)-2-四氢茚醇甲胺甲酰基]-1,1′-联二萘酚(V)作用吡唑啉-5-酮与硝基烯烃的反应,吡唑啉酮(3a～3l)产率为85%～92%。该反应具有反应条件温和、环境友好、操作简单等优点。Pryrazolone derivatives were synthesized by using binaphtyl carboxamides as catalysts,which possess tunable electronic effects.The results indicate that the reaction of pryrazoline derivative with nitroolefin can be catalyzed by idene alcohol-binaphy carboxamides at room temperature with a yield of 85%~92%.The procedure has the advantages of mild reaction conditions,environment-friendly,simplicity and so on.

关 键 词：吡唑啉-5-酮 硝基烯烃 吡唑酮啉衍生物 联二萘甲酰胺 

分 类 号：O626[理学—有机化学]