ATS药物依赖者血液传染性疾病危险因素分析  

Risk factors for blood borne diseases among ATS drug addicts

作　　者：张辉 牟玮 王文孟 谢娟 苏小芳 孙龙 ZHANG Hui;MOU Wei;WANG Wenmeng;XIE Juan;SU Xiaofang;SUN Long(Department of Vascular Surgery,First Affiliated Hospital of Military Medical University,Chongqing,400038;Department of Disease Prevention and Control,Center for Diseas Control and Prevention,Wanyuan City,Wanyuan,Sichuan,636350)

机构地区：[1]陆军军医大学第一附属医院血管外科,重庆400038 [2]四川省万源市疾病预防控制中心疾病预防控制科,万源636350

出　　处：《中国药物依赖性杂志》2019年第2期144-148,共5页Chinese Journal of Drug Dependence

摘　　要：目的:分析苯丙胺类兴奋剂(ATS)药物依赖者血液传染性疾病危险因素,为该人群病情监测和治疗提供有效依据。方法:收集万源市戒毒所2017年1月15日至2018年9月30日入所的289名ATS类戒毒人员的调查问卷和血清学样本,分析社会学指标的相关因素,所有数据使用SPSS 22. 0统计学软件进行分析。结果:289名ATS药物依赖者中,男性235名(81. 31%),女性54名(18. 69%),平均年龄36. 12±3. 67 a; ATS药物依赖者中感染HIV有14名(4. 84%),感染HCV103名(35. 64%),感染梅毒19名(6. 57%),两种病毒混合感染11名(3. 81%),三种病毒混合感染1名(0. 34%); ATS药物依赖者HIV感染的危险因素为注射吸毒(OR=5. 546)、商业性行为(OR=14. 546)、吸毒年限(OR=5. 019)和吸毒量(OR=14. 558); ATS药物依赖者HCV感染的危险因素为商业性行为(OR=4. 686)、吸毒年限(OR=5. 033)和吸毒量(OR=2. 711); ATS药物依赖者HCV感染的危险因素为初中及以下学历(OR=3. 873)、商业性行为(OR=4. 686)和吸毒量(OR=3. 291)。结论:ATS滥用是导致HIV和性传播疾病感染的重要危险因素。建议在ATS滥用群体加强宣传HIV、HCV及梅毒的基本知识,预防、干预吸毒人群经血和性途径传播感染性疾病。Objective: To analyze the risk factors of blood infectious diseases in drug addicts with amphetamine ( ATS),and to provide effective basis for disease monitoring and treatment.Methods: Questionnaire answers and serological samples were collected from 289 newly admitted ATS drug addicts from January 15,2017 to September 30,2018 in Wanyuan Drug Rehabilitation Institute. Relevant factors of sociological indicators were analyzed. Data management and statistical analysis were carried out using SPSS 22. 0. Results: Among 289 ATS drug addicts,235 ( 81. 31%) were males and 54 ( 18. 69%) were females,with an average age of 36. 12 + 3. 67 years;14 ( 4. 84%) were HIV-infected,103 ( 35. 64%) were HCV-infected,19 ( 6. 57%) were syphilis-infected,11 ( 3. 81%) were syphilis-infected,and 1 ( 0. 34%) were ATS drug-dependent. The risk factors of HIV infection in lairs were injecting drug use ( OR = 5. 546),commercial sexual behavior ( OR = 14. 546),drug use years ( OR = 5. 019) and drug use amount ( OR = 14. 558);the risk factors of HCV infection in ATS drug addicts were commercial sexual behavior ( OR = 4. 686),years of drug use ( OR = 5. 033) and drug use amount ( OR = 2. 711);the risk factors of HCV infection in ATS drug addicts were junior high school education and below.( OR = 3. 873),commercial sexual behavior ( OR = 4. 686) and drug abuse ( OR = 3. 291).Conclusion: ATS abuse is an important risk factor for HIV and STD infection. It is suggested that basic knowledge of HIV,HCV and syphilis should be strengthened among ATS abusers. We should prevent and intervene blood-borne and sexually transmitted infectious diseases among drug addicts.

关 键 词：ATS 药物依赖 经血传播疾病 危险因素 

分 类 号：R183.7[医药卫生—流行病学]