腹针联合中药周期疗法治疗肾虚排卵障碍性不孕疗效观察  

Therapeutic effects on infertility of ovulation failure in the patients with kidney deficiency treated with abdominal acupuncture and periodic therapy of Chinese herbal medicine

作　　者：郑晨思 罗丹 潘丽萍 黄健玲[2] 薄智云 ZHENG Chen-si;LUO Dan;PAN Li-ping;HUANG Jian-ling;BO Zhi-yun(Teaching and Research Office,Nanshan District Maternal and Child Care Service Center of Shenzhen City,Shenzhen 518000,Guangdong Province,China;Department of Giynecology,Guangdong Chinese Medicine Hospital,Guangzhou 510120;Bejing Bo's Medical Institute of Abdominal Acupuncture)

机构地区：[1]深圳市南山区妇幼保健院妇科教研室,广东深圳518000 [2]广东省中医院妇科,广州510120 [3]北京薄氏腹针医学研究院

出　　处：《中国针灸》2019年第5期482-486,共5页Chinese Acupuncture & Moxibustion

基　　金：深圳市南山区科技创新局科研项目:南科研卫2018056

摘　　要：目的:观察腹针联合中药周期疗法对肾虚型排卵障碍性不孕患者卵泡发育及子宫内膜的影响。方法:将84例肾虚型排卵障碍性不孕患者随机分为腹针联合中药组(针药组,27例)、腹针组(27例)和克罗米芬联合绒促组(西药组,30例)。针药组采用腹针联合中药周期治疗,腹针组采用单纯腹针治疗,西药组采用克罗米芬(CC)及注射用绒促性素(HCG)治疗,每个月经周期为1个疗程,连续治疗3个疗程,妊娠除外。观察各组治疗前后卵泡发育情况和子宫内膜厚度、形态,以及月经情况、中医症候评分,统计妊娠率,并评定临床疗效。结果:治疗后3组均不同程度恢复排卵,针药组排卵率59.3%(16/27),腹针组排卵率55.6%(15/27),西药组排卵率53.3%(16/30),3组间排卵率比较差异无统计学意义(P>0.05);针药组及腹针组治疗后围排卵期子宫内膜厚度均较治疗前增加(均P<0.05),针药组治疗后围排卵期子宫内膜厚度高于西药组(P<0.05);针药组及腹针组治疗后子宫内膜形态与治疗前比较,差异有统计学意义(P<0.05),针药组治疗后子宫内膜形态与西药组比较,差异有统计学意义(P<0.05);针药组及腹针组治疗后月经情况、中医症候评分较治疗前增加(均P<0.05),针药组治疗后月经情况评分高于西药组(P<0.05),针药组、腹针组治疗后中医症候评分高于西药组(均P<0.05);针药组总有效率为88.9%(24/27),腹针组为92.6%(25/27),均高于西药组的56.7%(17/30,均P<0.01)。针药组及腹针组未出现不良反应。结论:腹针联合中药周期疗法能改善肾虚型排卵障碍性不孕患者的月经情况及临床症状,疗效优于CC联合HCG,并能提高排卵率、改善围排卵期子宫内膜容受性以提高受孕率,无不良反应。Objective To observe the effects of abdominal acupuncture and the periodic therapy of Chinese herbal medicine on follicular development and endometrial receptivity in the patients with infertility induced by ovulation failure and differentiated as kidney deficiency in TCM.Methods A total of 84 patients with infertility induced by ovulation failure and differentiated as kidney deficiency were randomized into a combined therapy group(27 cases),an abdominal acupuncture group(27 cases)and a western medication group(30 cases).In the combined therapy group,abdominal acupuncture and the periodic treatment of Chinese herbal medicine was provided.In the abdominal acupuncture group,the simple abdominal acupuncture therapy was used.In the western medication group,clomiphene citrate(CC)and human chorionic gonadotrophin(HCG)prescribed.The treatment for one menstrual cycle was taken as one session and 3 sessions of treatment were required except the pregnancy.The folicle development,endometrial thickness and morphology,menstrual condition and TCM symptom score were observed before and after treatment in the three groups,and the clinical efficacy was evaluated.Results After treatment,the ovulation was recovered to different degrees in the three groups.The ovulation rate was59.3%(16/27)in the combined therapy group,55.6%(15/27)in the abdominal acupuncture group and 53.3%(16/30)in the western medication group.The difference was not significant in comparison among the three groups(P>0.05).After treatment,the endometrial thickness in the periovulatory period was increased as compared with the thickness before treatment in the combined therapy group and the abdominal acupuncture group(both P<0.05).After treatment,the endometrial thickness in the combined therapy group was higher than the western medication group(P<0.05).In comparison before and after treatment,the difference in the endometrial morphology was significant in the combined therapy group and the abdominal acupuncture group(both P<0.05).In comparison between the combined

关 键 词：排卵障碍性不孕 肾虚 腹针 中药 子宫内膜容受性 

分 类 号：R246.3[医药卫生—针灸推拿学]