股骨头坏死外科脱位入路打压植骨支撑术后超早期康复介入的保髋效果  

Hip-preserving efficacy of ultra-early rehabilitation after bone grafting through surgical dislocation approach in osteonecrosis of the femoral head

作　　者：陈海诚 袁颖嘉[1] 黄楚瑶 陈国铭 魏秋实[1] 陈聪 周驰[1] Chen Haicheng;Yuan Yingjia;Huang Chuyao;Chen Guoming;Wei Qiushi;Chen Cong;Zhou Chi(the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China;Clinical Medical College of Acupuncture, Moxibustion and Rehabilitation of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China;the First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China)

机构地区：[1]广州中医药大学第一附属医院,广东省广州市510405 [2]广州中医药大学针灸康复临床医学院,广东省广州市510405 [3]广州中医药大学第一临床医学院,广东省广州市510405

出　　处：《中国组织工程研究》2019年第24期3812-3818,共7页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金(81774339);项目参与人:周驰;青年科研人才培优项目(2015QN01);项目负责人:周驰~~

摘　　要：背景:研究发现股骨头坏死术后康复可促进恢复髋关节功能。目的:探讨股骨头坏死外科脱位入路打压植骨支撑术后超早期康复介入的保髋效果。方法:纳入中青年ARCOⅢ期股骨头缺血性坏死患者32例,随机分入试验组与对照组,每组16例。所有患者对治疗方案均知情同意,且得到医院伦理委员会批准(批件号:中医一附伦审科[2015]010号)。2组均接受常规的袁氏生脉成骨片药物治疗,联合采用经髋关节外科脱位入路打压植骨支撑术。对照组介入常规术后康复训练,试验组给予术后超早期康复训练流程。以疼痛目测类比评分和髋关节功能Harris评分评价关节恢复情况,以股骨头塌陷超过4 mm为终点事件,观察2组患者术后3,7,14 d的目测类比疼痛评分以及术后1,3,6个月的髋关节功能Harris评分。结果与结论:①目测类比评分:组内比较,术后3,7,14 d试验组目测类比评分逐渐降低(P <0.01),对照组目测类比评分也逐渐降低(P<0.01);组间比较,2组随着康复训练时间的增加术后疼痛减轻,术后7,14 d试验组目测类比评分均低于对照组(P <0.05);②髋关节功能Harris评分:组内比较,术后1,3,6个月试验组的Harris评分逐渐升高(P<0.01);组间比较,术后3,6个月试验组的Harris评分均高于对照组(P<0.01);③提示超早期康复介入能够在一定程度上改善股骨头坏死保髋术后的功能恢复速度和程度,术后标准化康复流程有助于促进股骨头坏死患者术后功能恢复。BACKGROUND: Postoperative rehabilitation of osteonecrosis of the femoral head has been shown to promote the recovery of hip joint function. OBJECTIVE: To explore the effect of ultra-early rehabilitation after bone grafting through surgical dislocation approach in osteonecrosis of the femoral head. METHODS: Thirty-two cases of young and middle-aged ARCOIII patients with avascular necrosis of femoral head were included, and randomly divided into the trial and control groups (n=16/group). All patients signed the informed consents and the study was approved by the Ethics Committee of the hospital, approval number:[2015]010. Two groups were treated with Yuan’s Shengmai Chenggu tablets and bone grafting via surgical hip dislocation. The control group received routine postoperative rehabilitation training, and the trial group was treated with ultra-early rehabilitation training. Joint recovery was evaluated with Visual Analogue Scale score, and Harris hip score. Femoral head collapse over 4 mm was the end event. The Visual Analogue Scale score at postoperative 3, 7 and 14 days, and Harris hip score at postoperative 1, 3 and 6 months were recorded. RESULTS AND CONCLUSION:(1) The Visual Analogue Scale score at postoperative 3, 7 and 14 days in the trial and control groups was decreased (both P < 0.01). The postoperative pain was alleviated with rehabilitation time in the two groups and the Visual Analogue Scale score at postoperative 7 and 14 days in the trial group was significantly lower than that in the control group (P < 0.05).(2) The Harris hip score at postoperative 1, 3 and 6 months in the trial group was gradually increased (P < 0.01). The Harris hip score at postoperative 3 and 6 months in the trial group was significantly higher than that in the control group (P < 0.01).(3) To conclude, ultra-early rehabilitation can improve the functional recovery after hip-preserving surgery of osteonecrosis of the femoral head to some extent, and standardized rehabilitation process can promote the postoperative functional r

关 键 词：股骨头坏死 植骨术 外科脱位入路 超早期康复 保髋效果 目测类比评分 Harris 评分 国家自然科学基金 

分 类 号：R459.9[医药卫生—治疗学]