探讨基因组DNA与蛋白质的心肾水火关系  

Understand Genomic DNA-Protein Collaboration Regarding Heart-Kidney Theory in Traditional Chinese Medicine

作　　者：孙雷 彭欣 秦林 Sun Lei;Peng Xbi;Qin Lin(School of Preclinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China)

机构地区：[1]山东中医药大学中医学院,济南250355

出　　处：《世界科学技术-中医药现代化》2019年第1期114-119,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：山东省科技厅自然科学基金面上项目(ZR2013HM053):血瘀出血相兼病证的微观机制与化瘀止血中药的干预研究;负责人:秦林

摘　　要：以中医心肾理论为指导,探讨基因组DNA与细胞中蛋白质间存在的互动关系。基因组DNA包藏数以万计的基因,并选择性地表达不同基因;蛋白质则通过直接或间接的方式影响基因组的表达。基因组DNA与蛋白质间所存在的这种适应生命活动需要的互动关系类似于中医学的心肾水火关系。结合神经系统中即早基因等例证,基因组DNA与蛋白质的互动关系有望为中医学"心肾水火"理论研究提供借鉴思路。In this discussion, from the view of water-fire theory in traditional Chinese Medicine(TCM), the collaboration of genomic DNA and proteins is analyzed. Thousands of genes are embedded in genomic DNA, and genes are expressed specifically to serve the life process. Proteins, as the product of genomic DNA, in turn, affect the expression of genes in the genomic DNA directly or indirectly. Thereby, genomic DNA and proteins are interactive and have the relation of heart-kidney coordination, waterexample, it is hoped that this discussion would help introducing biology into TCM research by understanding the interplay between genomic DNA and proteins in terms of heart-kidney coordination, water-fire coordination in TCM.

关 键 词：DNA 蛋白质 心肾 水火 即早基因 

分 类 号：R2-031[医药卫生—中西医结合]