脑胎盘率对预测胎儿生长受限的作用  

The role of cerebroplacental ratio in predicting fetal growth restriction

作　　者：张兰珍[1] 勾晨雨 刘晓岚 Zhang Lanzhen;Gou Chenyu;Liu Xiaolan(Department of Obstetrics and Gynecology,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China;Department of Obstetrics and Gynecology,The Sixth Hospital of Sun Yat-sen University,Guangzhou 510655,China)

机构地区：[1]广州医科大学附属第二医院妇产科,510260 [2]中山大学附属第六医院,广州510655

出　　处：《中华产科急救电子杂志》2019年第1期45-49,共5页Chinese Journal of Obstetric Emergency（Electronic Edition）

基　　金：广州市属高校科研计划项目(2012C028);广东省科技计划项目(20160218);广东省自然科学基金(2017A030310556)

摘　　要：目的探讨脑胎盘率(cerebroplacental ratio,CPR)预测胎儿生长受限(fetal growth restriction,FGR)的作用。方法对2015年1月至2017年12月在广州医科大学附属第二医院收治的52例FGR孕妇和同期正常产前检查分娩的49例孕妇临床资料进行回顾性分析。通过ROC曲线分析脑胎盘率、脐动脉、大脑中动脉血流对FGR不良妊娠结局预测,并计算曲线下面积(area under curve,AUC),对比各血流指标诊断FGR的灵敏度、特异度。结果孕28～31^(+6)周及孕32～36^(+6)周CPR指标较脐动脉及大脑中动脉血流指标更具有优越性,孕28～31^(+6)周及孕32～36^(+6)周曲线下面积值为0.82和0.96,截断值为1.74和1.59,灵敏度为96%和90%,特异度为79%和97%。结论 CPR可作为一项预测FGR的指标,具有临床意义。Objective To explore the role of cerebroplactic ratio(CPR)in predicting fetal growth restriction(FGR).Methods The clinical data of 52 pregnant women with FGR and 49 normal pregnant women,who were admitted to the Second Affiliated Hospital of Guangzhou Medical University from January 2015 to December 2017,were retrospectively analyzed.ROC curve was used to analyze the prediction of adverse pregnancy outcome of FGR by cerebral placenta rate,umbilical artery flow and middle cerebral artery blood flow.And the sensitivity and specificity of FGR diagnosed were analyzed by calculating area under curve(AUC)and comparing each blood flow index.Results The CPR at 28-31^+6 weeks of gestation and 32-36^+6 weeks of gestation were superior to those of umbilical artery and middle cerebral artery blood flow.AUC values at 28-31^+6 weeks of gestation and 32-36+6 weeks of gestation were 0.82 and 0.96,with cutoff values of 1.74 and 1.59.Their sensitivity was 96%and 90%,and the specificity is 79%and 97%,respectively.Conclusion CPR was clinically useful as a predictor of FGR.

关 键 词：胎儿生长迟缓 胎盘功能不全 大脑中动脉 超声检查 多普勒 彩色 

分 类 号：R714.5[医药卫生—妇产科学]